TI214_SPIOL
ID TI214_SPIOL Reviewed; 1833 AA.
AC Q9M3J5; Q9M3I3;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 2.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Spinacia oleracea (Spinach).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia.
OX NCBI_TaxID=3562;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Geant d'hiver, and cv. Monatol;
RX PubMed=11292076; DOI=10.1023/a:1006478403810;
RA Schmitz-Linneweber C., Maier R.M., Alcaraz J.-P., Cottet A., Herrmann R.G.,
RA Mache R.;
RT "The plastid chromosome of spinach (Spinacia oleracea): complete nucleotide
RT sequence and gene organization.";
RL Plant Mol. Biol. 45:307-315(2001).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC 481) of ycf1 in the inverted repeat (CAB88779).
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; AJ400848; CAB88779.1; -; Genomic_DNA.
DR EMBL; AJ400848; CAB88792.1; -; Genomic_DNA.
DR RefSeq; NP_054983.1; NC_002202.1.
DR RefSeq; NP_054996.1; NC_002202.1.
DR AlphaFoldDB; Q9M3J5; -.
DR STRING; 3562.Q9M3J5; -.
DR PRIDE; Q9M3J5; -.
DR GeneID; 2715687; -.
DR GeneID; 2715704; -.
DR KEGG; soe:2715687; -.
DR KEGG; soe:2715704; -.
DR OrthoDB; 53153at2759; -.
DR Proteomes; UP000054095; Chloroplast.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1833
FT /note="Protein TIC 214"
FT /id="PRO_0000217306"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 254..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1833 AA; 218472 MW; DACA271B5E931764 CRC64;
MIFQSFLLGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRAQVM EEGEEGTEKK
VSGTTGFIMG QLMMFISIYY TPLHLALGRP HTITVLALPY LLFHFFWNNH KHFFDYGSTS
RNSMRNLSIQ CVFLNNLIFQ LFNYFILPSS MLARLVNIYM FRCNNKMLFV TSSFVGWLIG
HILFMKWVGL VLVWIQQNNS IRSNKYLVSE LRNSMARIFS ILFFITCVYY LGRMPSPIFT
NKLKQMLETN EIEEETNLEI EKTSETKETK QEEEGFTEED PSPSLFSEEK EDPDKIDETE
KIRVNGKDKT KDEFHLKEAC YKNSPTSYSG NQDISKLEIL KKEKKILFWF QKPLIFLLFD
YKRWNRPMRY IKNNRFENAV RNEMSQYFFY TCQNDGKQRI SFTYPPSLSI FWEMIQRKIS
LATTEKFLYD DELYNYWIYT NEQKKNSLSN EFANRITVLD KGLFYIDVLD KKTRLCKSKN
EYLQKDHDPL LNGSYRGIIK KTLLPFINND ETTVKKLIDE IFINKIHSVL GNCNNYQEFE
YKKDPFKKNP ISSKIRHFVT LMSQFDGEST FNQKGISLLS EHKQICSEDP EIFFKFLVDT
IIADSFTQTI PKESIGIKEI SKKVPHWSYQ LIDESEQEEM ENEKQVSWPH QIRSRSGKEV
VFFTDKQENT DNPTPNTADI SEQADEVVLT RYPQESDFRR DIIKGSMRSQ RRKIVIWELF
QANIHSPLFL DRTNKSSFFS ITFSRLIKRI FKNYMGKNPE LDISNYKEEE LKKKEKAKEH
KKDKEKKQEQ IRLDIAETWD TIPGAQIIRS LILLTQSILR KYILLPLLIT GKNIGRILLF
QLPEWSDDFK EWTSEMHIKC TYNGVQLSEK EFPKNWLTDG MQIKILSPFC LKPWHKSMIR
PYHQDKKKKE QNQIDAFCFL TVVGLETDIP FGPPRKRPSF FQPIFKQLDK KIEKLIKGNF
QVRKRLKEKI LFFLKLQNET NNWIIEIFPF FKKIIRKMST VNTIGVFGLK EASSEIKSEK
DSRIKNHMIH ESSVQIRFLN QTNSSVTEKK MKDLANRTRI IKNKIEKISN DKLKMSPKKT
RYGTKNLGQI LKRRNARLIR NSNYILKFFR ERIYGDIFLY IINIPKINTQ LFLESTKNGI
DKSIYNNESI TKTNKNRIQF ISTINKKFLP FLSTSKNNSK IISDFSFLSQ AYVFYKLSQA
KILNLYKLRL VLQYRGISLF LKNEIKDFFG TQGITNSELK TKKLPNSGMN QWKNWLKLKN
NYQYNLSQLK WSRLVPQKWR NRVTEHCEVE NTNLYQNEEL INSKKHLLLL PDQKYNFQKN
YRYDVLSYKF FNYKNKNDSY RYSYGLPFQV NKNQEFSYTY NYNINNNKFI DMWWNIPISN
FSYLEKTKIM DIDKNIDRKY LDFKILDFSL RNKIDIEDWI DISTSINENT KTEPRNYQIV
EKINKKSLVY STIYQEIKQS DQKNKLFDWM GMNEKILSRP ISNLEFWFFS EFFSFYNAYK
MKPWVIPINL LFSNSNVSEK FSKNKSINRK KKTNPFIPSN EKKSFELENR NQDEKELVSK
EDLGSYVQEN YEKDIEEDYI SFIDIKKPIK QKQPKSVIEA EFDLFLKRYL LFQLKWADSL
NEKLMDNIQV YCLVLRLINP IEILISSIER KELSMDIMLD RKDFNCPNWK QKRVLIIEPI
RLSIRGDGQF LLYQTIGISL VHKSKHQNNQ KRYSENVDKK FLGERNKNNF DLLAPENLLS
PRRRRELRIL LCLNSRNNNG VNTNPMENRV KNCNQFFDEK KDLDRDKNTL RNLKFFLWPN
YRLEDLACMN RFWFDTNNGS RFSILRIHMY PQF
