ID   TI214_VITVI             Reviewed;        1893 AA.
AC   Q0ZIW0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Vitis vinifera (Grape).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Maxxa;
RX   PubMed=16603088; DOI=10.1186/1471-2148-6-32;
RA   Jansen R.K., Kaittanis C., Lee S.-B., Saski C., Tomkins J., Alverson A.J.,
RA   Daniell H.;
RT   "Phylogenetic analyses of Vitis (Vitaceae) based on complete chloroplast
RT   genome sequences: effects of taxon sampling and phylogenetic methods on
RT   resolving relationships among rosids.";
RL   BMC Evol. Biol. 6:32-32(2006).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; DQ424856; ABE47593.1; -; Genomic_DNA.
DR   RefSeq; YP_567136.1; NC_007957.1.
DR   AlphaFoldDB; Q0ZIW0; -.
DR   STRING; 29760.VIT_09s0054g00520.t01; -.
DR   PRIDE; Q0ZIW0; -.
DR   EnsemblPlants; Vitvi09g01359_t001; Vitvi09g01359_P001; Vitvi09g01359.
DR   GeneID; 4025074; -.
DR   Gramene; Vitvi09g01359_t001; Vitvi09g01359_P001; Vitvi09g01359.
DR   KEGG; vvi:4025074; -.
DR   eggNOG; ENOG502QSDY; Eukaryota.
DR   InParanoid; Q0ZIW0; -.
DR   OrthoDB; 53153at2759; -.
DR   Proteomes; UP000009183; Chloroplast.
DR   ExpressionAtlas; Q0ZIW0; baseline and differential.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1893
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262635"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1126..1146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          249..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..317
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1893 AA;  225561 MW;  DDA83B1E4615C8D7 CRC64;
     MILKSFLLGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRAQVM EEGEEGTEKK
     VSAITGFITG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWNNH KHFFDYGSTT
     RNSMRNLSIQ CVFLNNLIFQ LLNHFILPSS MLARLVNIYM FRCNNKMLFV TSSFVGWLIG
     HILFMKWVGL VLVWIRQNPS IRSNVLIRSN KYLVSELRNS MARIFSILLF ITCVYYLGRI
     PSPILTKKMK ETSETEERGE SEEETDVEIE RTSETKGTKQ EQERSTEEDP SPSLFSEEKE
     DPDKIDETEE IRVNGKEKTK DEFHFKETCY KNSPVYETSY LDGNQENSKL EILKEDEDNK
     NKKWFEKPLV TLLFDYKRWN RPLRYIKARF QIKKAVRNEM SQYFFYTCLS DGKQRISFTY
     PPSLSIFLEM IQRKMSLSTT ERLSYDELYN HWIYTNEQKE NTLRKEFITR IEALDNGSLT
     LDVLEKRTRL CNDATKKEYL PKIYDPFLNG PYRGTIKKMF SPSIINETSR ENSIEKFRIN
     KIYGILFAID YREFEHTFDR KSLSTKIGYF LNLINQFTIE SPSNLNLKRL SLFPEQGKVD
     SDSEDQAKFL NFFFDRVITD PKDQTIRKKS IGIKEISKKV PRWSYKLMKN EEEGETLVVY
     QEIRSRKSKH VVIFTDNQQN ADTYTANANK DIDNSEQTNE VALIRYSQQS DFRRDIIKGS
     MRAQRRKIVI RELFQANVHS PLFLDRIYKP IFFSFDISGL IKLIFENWKE KNKKLKIPNY
     AEEKTREKRQ KAKREEKARI KIAEVWDTVL FAQVIRGCLL LTQSIFRKYI ILPSLIIAKN
     IGRMLLFQSP EWSEDLKDWN REMHVKCTYN GVQLSETEFP QNWLRDGIQI KILFPFCLKP
     WHKPQERSLD KDSMKDKVKK FCFLTVWGME TDLPFGSPRK RPSFFKPILK ELEKRIRKFK
     NKCFLVLTVL KERTKLFIFL RVSKETKKWV IKSVLFINIK KIIKELLKIN PTLLFGLREV
     YESSETQKQK DSIINNQMIH KSSIQIRSMN WTNYSLTEKK VKDLTDRTST IRKKIEKIIK
     DKKKLFLTPE INISPNKASY NAKRLESQKS IWQILKRRNS RLIRKLHYFI KFFIERIYID
     ILLCLINIPR TNAQFFIEST KKIIDKYVYN NERNQKRIGK PNQKKIHFIS IIKRSVSSIS
     NKSSQIFCDL SSLSQAYVFY KLSQTQVINL YKLRSVLQYN GTSLFLKNER KDYFGFGAHE
     IFHYELRHKK LRNSGMNQWK NWLRGHYQYK YLSPIIWSRL VPQKWRNRVN QHCVAQNQNK
     DLSKWDLSQK DQLIHYNKQN DYEADSLTNQ KENFKKHYRY DLLSYKYINY EDKNDSYIYG
     SPLQVNNNQD ISYNYNTHKR KFFDMLEGIP INNYLGEDDI MYIEYIKKNP DRKYFDWKIL
     HFCFRKKVDI EVWINTSINS NKNTKTGSNN YQIIDKKGLF YLTQDQEIKP SNQKDLFDWM
     GMNEEILNRS ISNLEPWFFP EFVLLYNTYK MKPWVIPIKL LLLNFNGNKN YSKNRNSNRK
     QKGNLFISSN EKKLLKLENR NQEEKESAGQ VDLGSDVQNQ GNLESVLSNH EKDIEEDYAG
     SDSDMQKRTK KKQFKNHTEA ELDLFLKRYL LFQLRWDDSL NQKMINNIKV YCLLLRLINP
     REICISAIQR GEMSLDLIPV HKDLTLTELM KMKRGIFIIE PIRLSVKNDG QFIMYQTIGI
     SLVHKSKYQT NQRYREERYV DNKNCDKFSA RCQKMIGNKD KNHYDLLVPE NILSPRRRRK
     FRILICFNLR NRSGVARNPV FCNGNSCNKF LDENKHLDRD KNQLIKLKKL KLFLWPNYRL
     EDLACMNRYW FDTNNGSCFS MIRIHMYPRL KIR