ID   TIDC1_DANRE             Reviewed;         292 AA.
AC   Q568N3;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Complex I assembly factor TIMMDC1, mitochondrial;
DE   AltName: Full=Translocase of inner mitochondrial membrane domain-containing protein 1;
DE            Short=TIMM domain containing-protein 1;
GN   Name=timmdc1; ORFNames=zgc:110196;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Chaperone protein involved in the assembly of the
CC       mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
CC       Participates in constructing the membrane arm of complex I (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with the intermediate 315 kDa subcomplex of
CC       incompletely assembled complex I. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Tim17/Tim22/Tim23 family. {ECO:0000305}.
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DR   EMBL; BC092788; AAH92788.1; -; mRNA.
DR   RefSeq; NP_001017828.1; NM_001017828.1.
DR   AlphaFoldDB; Q568N3; -.
DR   STRING; 7955.ENSDARP00000069984; -.
DR   PaxDb; Q568N3; -.
DR   GeneID; 550526; -.
DR   KEGG; dre:550526; -.
DR   CTD; 51300; -.
DR   ZFIN; ZDB-GENE-050417-369; timmdc1.
DR   eggNOG; KOG4608; Eukaryota.
DR   InParanoid; Q568N3; -.
DR   OrthoDB; 1366254at2759; -.
DR   PhylomeDB; Q568N3; -.
DR   Reactome; R-DRE-6799198; Complex I biogenesis.
DR   PRO; PR:Q568N3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Chaperone; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..292
FT                   /note="Complex I assembly factor TIMMDC1, mitochondrial"
FT                   /id="PRO_0000252482"
FT   TRANSMEM        146..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   292 AA;  32372 MW;  7415A71765BF1466 CRC64;
     MCTAVRQDLS LKCGGTDVKQ PGDSQPGHLR ALLGFTLPSV YASDSSTQIL PKHIGKPEFP
     DTGWDRIKDL FYNVEGQYTE ELRNVVKSGI ASAIVGMIYG GLPGARHARQ RFIQCSQAEI
     YRNRVDAVRA AHNAAIRGFL RFGWRWSWRV AAFVTLFNTV NTGLTVYRDQ NALSHFAVSG
     AVTGGVFRLN LGLRGLLSGT IIGVILGFPA GVLILGLQNL GGETMRDKRR RERRELHELR
     VTEWNARLKV TDDLIGEMSS LKHQDSEIDL QQVEELLSQP RNGNAAKGPY NQ