ID   TIDC1_XENLA             Reviewed;         256 AA.
AC   Q5XK94;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Complex I assembly factor TIMMDC1, mitochondrial;
DE   AltName: Full=Translocase of inner mitochondrial membrane domain-containing protein 1;
DE            Short=TIMM domain containing-protein 1;
GN   Name=timmdc1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Chaperone protein involved in the assembly of the
CC       mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
CC       Participates in constructing the membrane arm of complex I (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with the intermediate 315 kDa subcomplex of
CC       incompletely assembled complex I. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Tim17/Tim22/Tim23 family. {ECO:0000305}.
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DR   EMBL; BC083018; AAH83018.1; -; mRNA.
DR   RefSeq; NP_001088139.1; NM_001094670.2.
DR   RefSeq; XP_018100708.1; XM_018245219.1.
DR   RefSeq; XP_018100709.1; XM_018245220.1.
DR   RefSeq; XP_018100710.1; XM_018245221.1.
DR   AlphaFoldDB; Q5XK94; -.
DR   MaxQB; Q5XK94; -.
DR   GeneID; 494845; -.
DR   KEGG; xla:494845; -.
DR   CTD; 494845; -.
DR   Xenbase; XB-GENE-6255068; timmdc1.L.
DR   OMA; WQYKWRL; -.
DR   OrthoDB; 1366254at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 494845; Expressed in testis and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Chaperone; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..256
FT                   /note="Complex I assembly factor TIMMDC1, mitochondrial"
FT                   /id="PRO_0000252481"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   256 AA;  28246 MW;  9CE85C21A1C72AF1 CRC64;
     MAQSDPPKSP DPPLPTSIRN PQTPESGWDR IRELFQPNEQ GHYPEEVGSI VKSAVTGALL
     GGIYGGLPAA RHSKERYIQQ SQAQIYQHRV EAVRSAHNAA LRGFIRYGWR WGWRVAAFVT
     IFNSVSTGLT VYRDKLALSH YAAAGAVTGG LFRLNLGLVG LLSGSLIGAA LGVPAGALIS
     GLQSISGESI REKKRRERQE LYENKVQEWS ARLQVTDEVL EEMETSQQDP LEQQVEKIQE
     LLQLPRNPAV SPKEGR