ID   TIGD5_BOVIN             Reviewed;         643 AA.
AC   G3MY25;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 2.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Tigger transposable element-derived protein 5;
GN   Name=TIGD5;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
RA   Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D.,
RA   Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G.,
RA   Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
RT   "A whole-genome assembly of the domestic cow, Bos taurus.";
RL   Genome Biol. 10:R42.01-R42.10(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the tigger transposable element derived protein
CC       family. {ECO:0000305}.
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DR   EMBL; DAAA02037468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005192620.2; XM_005192563.3.
DR   RefSeq; XP_005215336.1; XM_005215279.3.
DR   AlphaFoldDB; G3MY25; -.
DR   SMR; G3MY25; -.
DR   STRING; 9913.ENSBTAP00000054451; -.
DR   PaxDb; G3MY25; -.
DR   PRIDE; G3MY25; -.
DR   GeneID; 101903505; -.
DR   KEGG; bta:101903505; -.
DR   CTD; 84948; -.
DR   eggNOG; KOG3105; Eukaryota.
DR   HOGENOM; CLU_018294_1_1_1; -.
DR   InParanoid; G3MY25; -.
DR   OrthoDB; 1343623at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR   InterPro; IPR007889; HTH_Psq.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF04218; CENP-B_N; 1.
DR   Pfam; PF03184; DDE_1; 1.
DR   Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR   SMART; SM00674; CENPB; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   PROSITE; PS51253; HTH_CENPB; 1.
DR   PROSITE; PS50960; HTH_PSQ; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..643
FT                   /note="Tigger transposable element-derived protein 5"
FT                   /id="PRO_0000416767"
FT   DOMAIN          52..103
FT                   /note="HTH psq-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00320"
FT   DOMAIN          117..190
FT                   /note="HTH CENPB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00583"
FT   DOMAIN          238..358
FT                   /note="DDE-1"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        79..99
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   DNA_BIND        150..183
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          197..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          366..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..49
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        370..387
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   643 AA;  70331 MW;  167DEB9E7A96DC9D CRC64;
     MYSAGPPAVP APRRCRRPPP GRPMQPPRPP APAPVPAARP PPPAPGPRPR VAVKMAFRKA
     YSIKDKLQAI ERVKGGERQA SVCRDFGVPG GTLRGWLKDE PKLRWFLEQL GGEVGTQRKK
     MRLANEEEID RAVYSWFLAL RQHGVPLSGP LIQAQAEAFA RQIYGPECTF KASHGWFWRW
     QKRHGISSQR IYGEAEPVAA GPAPGPPVKQ EPAQPTRAGP LPDRAASTPA PAEGGYGDEQ
     IYNANVTGLY WKLLPEQAAP VGAGGCGRRW RGDRVTVLLA ANLTGSHKLK PLVIGQLPDP
     PSLRHHNQDK FPASYRYSPD AWLSRPLLRG WFFEEFVPGV RRYLRRSCLQ QKAVLLVAHP
     PCPSSEARMP ALEESEETRR RCRPEPTGPP EELQTPDGAV RVLFLCRGSG RAHIPAPLEQ
     GVVAAFKQLY KRELLRLAVS CAGGSPLDFM RSFMLKDMLY LAGLSWDLVQ AGSIERCWLL
     GLRAAFEPRP VEERAGQPAG QAEEAAEHSR VLSDLTHLAA LAYKRLAPEE VAEWLHLDDD
     GGLPDGGRED WGPSRPPVLV PGGPLLPASL PSAVAGGAEE EEEEAIPTAG EAVRGLETAL
     RWLETQDPRE VGPLKLVQLR SLISTARRLG GIGPSPMVPD DGL