ID   TIGD5_RAT               Reviewed;         642 AA.
AC   B1WC39;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Tigger transposable element derived 5;
GN   Name=Tigd5;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the tigger transposable element derived protein
CC       family. {ECO:0000305}.
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DR   EMBL; CH473950; EDM16036.1; -; Genomic_DNA.
DR   EMBL; BC161993; AAI61993.1; -; mRNA.
DR   RefSeq; NP_001119740.1; NM_001126268.2.
DR   AlphaFoldDB; B1WC39; -.
DR   SMR; B1WC39; -.
DR   STRING; 10116.ENSRNOP00000066232; -.
DR   PaxDb; B1WC39; -.
DR   PRIDE; B1WC39; -.
DR   Ensembl; ENSRNOT00000056527; ENSRNOP00000066232; ENSRNOG00000008686.
DR   GeneID; 300034; -.
DR   KEGG; rno:300034; -.
DR   UCSC; RGD:1311576; rat.
DR   CTD; 84948; -.
DR   RGD; 1311576; Tigd5.
DR   eggNOG; KOG3105; Eukaryota.
DR   HOGENOM; CLU_018294_1_1_1; -.
DR   InParanoid; B1WC39; -.
DR   OMA; PACYRYS; -.
DR   OrthoDB; 1343623at2759; -.
DR   PhylomeDB; B1WC39; -.
DR   PRO; PR:B1WC39; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Proteomes; UP000234681; Chromosome 7.
DR   Bgee; ENSRNOG00000008686; Expressed in thymus and 19 other tissues.
DR   Genevisible; B1WC39; RN.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR   InterPro; IPR007889; HTH_Psq.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF04218; CENP-B_N; 1.
DR   Pfam; PF03184; DDE_1; 1.
DR   Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR   SMART; SM00674; CENPB; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   PROSITE; PS51253; HTH_CENPB; 1.
DR   PROSITE; PS50960; HTH_PSQ; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..642
FT                   /note="Tigger transposable element derived 5"
FT                   /id="PRO_0000416769"
FT   DOMAIN          56..107
FT                   /note="HTH psq-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00320"
FT   DOMAIN          121..194
FT                   /note="HTH CENPB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00583"
FT   DOMAIN          239..364
FT                   /note="DDE-1"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        83..103
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   DNA_BIND        154..187
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          198..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..583
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..53
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   642 AA;  70268 MW;  8ACF932CFBB2C89E CRC64;
     MYPASPSAGP ALHPVPHRAR LPRPRCLAEP PRSPAPGPGS TARPPPPAPG PRPRVAVKMT
     FRKAYSIKDK LQAIERVKGG ERQASVCRDF GVPGGTLRGW LKDEPKLRWF LDQLGGEVGT
     QRKKMRLANE EEIDRAVYSW FLTLRQHGVP LSGPVIQAQA EAFARQIYGP ECTFKASHGW
     FWRWQKRHGI SSQRIYGEAE PPVAGPAPVK EEPAQPSSAG LLLDGTPATL PHSEGGYGDE
     QIYNANVTGL YWRLLPEQNA TPGTGDSREP GECSRRWCSD RVTVLLAANL TGSHKLKPLV
     IGQLPDPPSL RHHNQDKFPA SYRYSPDAWL SRPLLRGWFF EEFVPGVKRY LRRSCLQQKA
     VLLVAHPPCP SWTTSMPAVE ESEGTPRQCQ PELLGSPEEL QTPDGAVRVL FLSRGNSRAH
     IPAPLEHGVV AAFKHLYKRE LLRLAVSCAS GSPLDFMRSF MLKDMLYLAG LSWDLVQAGS
     IERCWLLGLR AAFEPGQQPA HQVEEAAEHS RMLSDLTHLA ALAYKRLAPE EVAEWLHLDD
     DGGLPEGCGE EVAPAAPPSP ASLPSSIGAG EEEEEEATEQ GGVLVPTAGE AVWGLETALR
     WLESQDPREV GPLRLVQLRS LITMARRLGG IGPSAAASDD GV