ID   BSAZ_BURTA              Reviewed;         381 AA.
AC   Q2T713;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Secretion apparatus protein BsaZ;
GN   Name=bsaZ; OrderedLocusNames=BTH_II0839;
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS   E264).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- FUNCTION: Part of the bsa type III secretion system, is involved in the
CC       intracellular replication of invading bacteria inside the host cell.
CC       Probably necessary for the lysis of the vacuole membrane and escape
CC       into the host cell cytoplasm (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC       {ECO:0000305}.
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DR   EMBL; CP000085; ABC34818.1; -; Genomic_DNA.
DR   RefSeq; WP_009896146.1; NZ_CP008786.1.
DR   AlphaFoldDB; Q2T713; -.
DR   SMR; Q2T713; -.
DR   EnsemblBacteria; ABC34818; ABC34818; BTH_II0839.
DR   KEGG; bte:BTH_II0839; -.
DR   HOGENOM; CLU_041013_1_3_4; -.
DR   OMA; QPNPGAY; -.
DR   OrthoDB; 1424100at2; -.
DR   Proteomes; UP000001930; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.1690.10; -; 1.
DR   InterPro; IPR006307; BsaZ.
DR   InterPro; IPR006135; T3SS_substrate_exporter.
DR   InterPro; IPR029025; T3SS_substrate_exporter_C.
DR   PANTHER; PTHR30531; PTHR30531; 1.
DR   Pfam; PF01312; Bac_export_2; 1.
DR   PRINTS; PR00950; TYPE3IMSPROT.
DR   SUPFAM; SSF160544; SSF160544; 1.
DR   TIGRFAMs; TIGR01404; FlhB_rel_III; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Virulence.
FT   CHAIN           1..381
FT                   /note="Secretion apparatus protein BsaZ"
FT                   /id="PRO_0000344018"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          343..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   381 AA;  41867 MW;  1FCE8F9668AFB83E CRC64;
     MAEKTEKPTA KKLRDAAKKG QTFKARDIVA LVVIATGALS APALVDLTRV AAEFTRIAST
     GAQPNPGAYA LAWAKLFLRI AAPFVLLCAA VGALPSLVQS RFTLAVESIR FDLTALDPVK
     GMKRLFSWRS VKDAVKALLY VGVFAITVRV FADLYHHDVF GLFRARPALL GHMWIVLTVR
     LVLLFLLCAL PVLIVDAAVE YFLYHRELKM DKHEVKQEYK ESEGNHEIKS KRREIHQELL
     SEEIKANVEQ SDFIVANPTH IAIGIYVNPD IVPIPFVSVR ETNARALAVI RHAEACGVPV
     VRNVALARSI YRNSPRRYSF VNQDDIDGVM RVLIWLKEVE AANRGGPPRE MPPEATHAPD
     AHGGDAASGG ATSAQAGERN A