BSC1_YEAST
ID BSC1_YEAST Reviewed; 328 AA.
AC Q12140; D6VRV7;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Bypass of stop codon protein 1;
GN Name=BSC1; OrderedLocusNames=YDL037C; ORFNames=D2734;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9046088;
RX DOI=10.1002/(sici)1097-0061(199701)13:1<65::aid-yea50>3.0.co;2-t;
RA Saren A.-M., Laamanen P., Lejarcegui J.B., Paulin L.;
RT "The sequence of a 36.7 kb segment on the left arm of chromosome IV from
RT Saccharomyces cerevisiae reveals 20 non-overlapping open reading frames
RT (ORFs) including SIT4, FAD1, NAM1, RNA11, SIR2, NAT1, PRP9, ACT2 and MPS1
RT and 11 new ORFs.";
RL Yeast 13:65-71(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169867;
RA Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G.,
RA Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C.,
RA Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F.,
RA Delaveau T., del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M.,
RA Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T.,
RA Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C.,
RA Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S.,
RA Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L.,
RA Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H.,
RA Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M.,
RA Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M.,
RA Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A.,
RA Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G.,
RA Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E.,
RA Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S.,
RA Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D.,
RA Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V.,
RA Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E.,
RA Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M.,
RA Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D.,
RA Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A.,
RA Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R.,
RA Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T.,
RA Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L.,
RA Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E.,
RA Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L.,
RA Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M.,
RA Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K.,
RA Mewes H.-W., Zollner A., Zaccaria P.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
RL Nature 387:75-78(1997).
RN [4]
RP GENE NAME.
RX PubMed=12711673; DOI=10.1093/nar/gkg330;
RA Namy O., Duchateau-Nguyen G., Hatin I., Hermann-Le Denmat S., Termier M.,
RA Rousset J.-P.;
RT "Identification of stop codon readthrough genes in Saccharomyces
RT cerevisiae.";
RL Nucleic Acids Res. 31:2289-2296(2003).
CC -!- MISCELLANEOUS: Open reading frame exhibits genomic organization
CC compatible with a translational readthrough-dependent mode of
CC expression.
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DR EMBL; Z71781; CAA96452.1; -; Genomic_DNA.
DR EMBL; Z74085; CAA98596.1; -; Genomic_DNA.
DR EMBL; BK006938; DAA11817.1; -; Genomic_DNA.
DR PIR; S67570; S67570.
DR RefSeq; NP_010247.1; NM_001180096.1.
DR AlphaFoldDB; Q12140; -.
DR SMR; Q12140; -.
DR BioGRID; 32021; 50.
DR DIP; DIP-5600N; -.
DR IntAct; Q12140; 1.
DR MINT; Q12140; -.
DR STRING; 4932.YDL037C; -.
DR PaxDb; Q12140; -.
DR EnsemblFungi; YDL037C_mRNA; YDL037C; YDL037C.
DR GeneID; 851524; -.
DR KEGG; sce:YDL037C; -.
DR SGD; S000002195; BSC1.
DR VEuPathDB; FungiDB:YDL037C; -.
DR eggNOG; ENOG502S1H2; Eukaryota.
DR GeneTree; ENSGT00940000176775; -.
DR HOGENOM; CLU_070636_0_0_1; -.
DR InParanoid; Q12140; -.
DR OMA; NILHYDM; -.
DR BioCyc; YEAST:G3O-29461-MON; -.
DR PRO; PR:Q12140; -.
DR Proteomes; UP000002311; Chromosome IV.
DR RNAct; Q12140; protein.
DR InterPro; IPR018789; Flo11.
DR Pfam; PF10182; Flo11; 1.
DR SMART; SM01213; Flo11; 1.
DR PROSITE; PS51824; FLO11; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..328
FT /note="Bypass of stop codon protein 1"
FT /id="PRO_0000064992"
FT DOMAIN 1..155
FT /note="Flo11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01168"
FT REGION 168..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 34796 MW; 32A726CB6E6E0BD3 CRC64;
MSQQNILHYD MDVTSVSWVK DNTYQITIHV KAVKDIPLKY LWSLKIIGVN GPSSTVQLYG
KNEKTYLISD PTDFTSTFQV YAYPSSDGCT VWMPNFQIQF EYLQGDAAQY WQTWQWGTTT
FDLSTGCNNY DNQGHSQTDF PGFYWTYQCK GNNDGTCTKA SSSSITTSSI TTSSTTTSST
TTSSTTTSSS TTSSSTTSSS TTSSSTTSSS TTSSSTTSSS TTSSSTTSSS TTSSSTTSSS
TTSSSTKTST TTSSTVKSSS TTSIDFTTSV DSHTSSSVAD IYRSRTSTDV TTLAASTSPF
SSFTSSDSSS SSDVTSSTIQ TTSVDPTT
