ID   BSDC1_DANRE             Reviewed;         412 AA.
AC   A2BIJ3; Q68EL9;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=BSD domain-containing protein 1;
GN   Name=bsdc1; ORFNames=si:ch211-51n3.2, zgc:100785;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-308, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RC   TISSUE=Embryo;
RX   PubMed=18307296; DOI=10.1021/pr700667w;
RA   Lemeer S., Pinkse M.W.H., Mohammed S., van Breukelen B., den Hertog J.,
RA   Slijper M., Heck A.J.R.;
RT   "Online automated in vivo zebrafish phosphoproteomics: from large-scale
RT   analysis down to a single embryo.";
RL   J. Proteome Res. 7:1555-1564(2008).
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DR   EMBL; BX936305; CAM12911.1; -; Genomic_DNA.
DR   EMBL; BC080207; AAH80207.1; -; mRNA.
DR   RefSeq; NP_001004108.2; NM_001004108.2.
DR   AlphaFoldDB; A2BIJ3; -.
DR   STRING; 7955.ENSDARP00000003318; -.
DR   iPTMnet; A2BIJ3; -.
DR   PaxDb; A2BIJ3; -.
DR   Ensembl; ENSDART00000005195; ENSDARP00000003318; ENSDARG00000052623.
DR   GeneID; 794882; -.
DR   KEGG; dre:794882; -.
DR   CTD; 55108; -.
DR   ZFIN; ZDB-GENE-040905-1; bsdc1.
DR   eggNOG; KOG2690; Eukaryota.
DR   GeneTree; ENSGT00390000009361; -.
DR   HOGENOM; CLU_053864_0_0_1; -.
DR   InParanoid; A2BIJ3; -.
DR   OMA; PCANVKF; -.
DR   OrthoDB; 787655at2759; -.
DR   PhylomeDB; A2BIJ3; -.
DR   TreeFam; TF313210; -.
DR   PRO; PR:A2BIJ3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 13.
DR   Bgee; ENSDARG00000052623; Expressed in muscle tissue and 28 other tissues.
DR   ExpressionAtlas; A2BIJ3; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   Gene3D; 1.10.3970.10; -; 1.
DR   InterPro; IPR005607; BSD_dom.
DR   InterPro; IPR035925; BSD_dom_sf.
DR   Pfam; PF03909; BSD; 1.
DR   SMART; SM00751; BSD; 1.
DR   SUPFAM; SSF140383; SSF140383; 1.
DR   PROSITE; PS50858; BSD; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..412
FT                   /note="BSD domain-containing protein 1"
FT                   /id="PRO_0000282642"
FT   DOMAIN          145..197
FT                   /note="BSD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00036"
FT   REGION          208..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        255..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..323
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..348
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..370
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         308
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18307296"
FT   CONFLICT        236
FT                   /note="L -> S (in Ref. 2; AAH80207)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        257
FT                   /note="D -> G (in Ref. 2; AAH80207)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        333
FT                   /note="A -> V (in Ref. 2; AAH80207)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   412 AA;  45366 MW;  E69D11CDE44C3AD6 CRC64;
     MADGEGGWWG GWLTQSFQSV KDKSAEAYEF IKRDLTEFSS VVQHDTACSV VATANAIKSK
     LAVEGSSETT EKVKKGITNI LGVITDTLAP PPDKTIDCDV ITLVATPTGT TEVYDSGKAR
     LYSLQADPAT YCNEPDGPPQ QFDSWLSTFS LEERKAEISE LLVSSPAIRA LYTKMVPAAV
     AHAEFWQRYF YKVFQLEQEE ARRVALKQRA EQTDHSESLG WEEEDEEGEF LGATSLSRLD
     FTPPVEESRV PAVTVADTPE SSSPPQAVAS LSNVASDVTP SVSSDSVSFP TQIENQAESV
     TIRVTQPSPA ADELSQKLSD TGLQETFPEE RPAPREETAR EDMAQDLRVF ELNSDSGKST
     PSNNGKKGSS TDVSEDWEKD FDLDMTEEEV QMALSKVDAT EELEDEDWEN WE