BSDC1_HUMAN
ID BSDC1_HUMAN Reviewed; 430 AA.
AC Q9NW68; B4DMS7; B4DTI7; B4DTP7; B4E2X8; Q49AT8; Q68DY6; Q6IAA3; Q6MZK1;
AC Q6UXS1; Q9HAL9;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=BSD domain-containing protein 1;
GN Name=BSDC1; ORFNames=UNQ2494/PRO5781;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
RX PubMed=12975309; DOI=10.1101/gr.1293003;
RA Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
RA Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
RA Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
RA Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
RA Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
RA Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
RT "The secreted protein discovery initiative (SPDI), a large-scale effort to
RT identify novel human secreted and transmembrane proteins: a bioinformatics
RT assessment.";
RL Genome Res. 13:2265-2270(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 4; 5; 7; 8 AND 9).
RC TISSUE=Brain, Embryo, Placenta, and Uterus;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.;
RT "Cloning of human full open reading frames in Gateway(TM) system entry
RT vector (pDONR201).";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4).
RC TISSUE=Prostate;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D.,
RA Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A.,
RA Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [8]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-92 AND SER-418, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.;
RT "Quantitative phosphoproteomics reveals widespread full phosphorylation
RT site occupancy during mitosis.";
RL Sci. Signal. 3:RA3-RA3(2010).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [10]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21406692; DOI=10.1126/scisignal.2001570;
RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T.,
RA Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.;
RT "System-wide temporal characterization of the proteome and phosphoproteome
RT of human embryonic stem cell differentiation.";
RL Sci. Signal. 4:RS3-RS3(2011).
RN [11]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166; THR-356; SER-387 AND
RP SER-388, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Erythroleukemia;
RX PubMed=23186163; DOI=10.1021/pr300630k;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
RN [12]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-387, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L.,
RA Ye M., Zou H.;
RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver
RT phosphoproteome.";
RL J. Proteomics 96:253-262(2014).
CC -!- INTERACTION:
CC Q9NW68; P54852: EMP3; NbExp=3; IntAct=EBI-721848, EBI-3907816;
CC Q9NW68; Q9H0R8: GABARAPL1; NbExp=3; IntAct=EBI-721848, EBI-746969;
CC Q9NW68; P60520: GABARAPL2; NbExp=3; IntAct=EBI-721848, EBI-720116;
CC Q9NW68; Q9UL33-2: TRAPPC2L; NbExp=3; IntAct=EBI-721848, EBI-11119202;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=9;
CC Name=1;
CC IsoId=Q9NW68-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9NW68-2; Sequence=VSP_024222, VSP_024223;
CC Name=3;
CC IsoId=Q9NW68-3; Sequence=VSP_024218, VSP_024224;
CC Name=4;
CC IsoId=Q9NW68-4; Sequence=VSP_024217, VSP_024224;
CC Name=5;
CC IsoId=Q9NW68-5; Sequence=VSP_024219, VSP_024220;
CC Name=6;
CC IsoId=Q9NW68-6; Sequence=VSP_024216, VSP_024221, VSP_024224;
CC Name=7;
CC IsoId=Q9NW68-7; Sequence=VSP_024218;
CC Name=8;
CC IsoId=Q9NW68-8; Sequence=VSP_041673;
CC Name=9;
CC IsoId=Q9NW68-9; Sequence=VSP_041672;
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DR EMBL; AY358230; AAQ88597.1; -; mRNA.
DR EMBL; AK001138; BAA91517.1; -; mRNA.
DR EMBL; AK021440; BAB13825.1; -; mRNA.
DR EMBL; AK297604; BAG59989.1; -; mRNA.
DR EMBL; AK300231; BAG61999.1; -; mRNA.
DR EMBL; AK300306; BAG62059.1; -; mRNA.
DR EMBL; AK304477; BAG65290.1; -; mRNA.
DR EMBL; CR457252; CAG33533.1; -; mRNA.
DR EMBL; BX641056; CAE46029.1; -; mRNA.
DR EMBL; CR749228; CAH18084.1; -; mRNA.
DR EMBL; AL109945; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471059; EAX07526.1; -; Genomic_DNA.
DR EMBL; BC026322; AAH26322.1; -; mRNA.
DR EMBL; BC028381; AAH28381.1; -; mRNA.
DR CCDS; CCDS363.2; -. [Q9NW68-1]
DR CCDS; CCDS44101.1; -. [Q9NW68-9]
DR CCDS; CCDS44102.1; -. [Q9NW68-8]
DR CCDS; CCDS44103.1; -. [Q9NW68-7]
DR CCDS; CCDS72752.1; -. [Q9NW68-3]
DR RefSeq; NP_001137360.1; NM_001143888.2. [Q9NW68-7]
DR RefSeq; NP_001137361.1; NM_001143889.2. [Q9NW68-8]
DR RefSeq; NP_001137362.1; NM_001143890.2. [Q9NW68-9]
DR RefSeq; NP_001287887.1; NM_001300958.1. [Q9NW68-3]
DR RefSeq; NP_060515.3; NM_018045.7. [Q9NW68-1]
DR AlphaFoldDB; Q9NW68; -.
DR BioGRID; 120418; 26.
DR IntAct; Q9NW68; 15.
DR MINT; Q9NW68; -.
DR STRING; 9606.ENSP00000344816; -.
DR GlyGen; Q9NW68; 1 site, 1 O-linked glycan (1 site).
DR iPTMnet; Q9NW68; -.
DR PhosphoSitePlus; Q9NW68; -.
DR BioMuta; BSDC1; -.
DR DMDM; 74753009; -.
DR EPD; Q9NW68; -.
DR jPOST; Q9NW68; -.
DR MassIVE; Q9NW68; -.
DR MaxQB; Q9NW68; -.
DR PaxDb; Q9NW68; -.
DR PeptideAtlas; Q9NW68; -.
DR PRIDE; Q9NW68; -.
DR ProteomicsDB; 82899; -. [Q9NW68-1]
DR ProteomicsDB; 82900; -. [Q9NW68-2]
DR ProteomicsDB; 82901; -. [Q9NW68-3]
DR ProteomicsDB; 82902; -. [Q9NW68-4]
DR ProteomicsDB; 82903; -. [Q9NW68-5]
DR ProteomicsDB; 82904; -. [Q9NW68-6]
DR ProteomicsDB; 82905; -. [Q9NW68-7]
DR ProteomicsDB; 82906; -. [Q9NW68-8]
DR ProteomicsDB; 82907; -. [Q9NW68-9]
DR Antibodypedia; 16954; 120 antibodies from 20 providers.
DR DNASU; 55108; -.
DR Ensembl; ENST00000341071.11; ENSP00000344816.7; ENSG00000160058.19. [Q9NW68-3]
DR Ensembl; ENST00000419121.6; ENSP00000405752.2; ENSG00000160058.19. [Q9NW68-8]
DR Ensembl; ENST00000444377.5; ENSP00000414103.1; ENSG00000160058.19. [Q9NW68-2]
DR Ensembl; ENST00000446293.6; ENSP00000397759.2; ENSG00000160058.19. [Q9NW68-7]
DR Ensembl; ENST00000455895.7; ENSP00000412173.2; ENSG00000160058.19. [Q9NW68-1]
DR Ensembl; ENST00000526031.5; ENSP00000432382.1; ENSG00000160058.19. [Q9NW68-9]
DR GeneID; 55108; -.
DR KEGG; hsa:55108; -.
DR MANE-Select; ENST00000455895.7; ENSP00000412173.2; NM_018045.8; NP_060515.3.
DR UCSC; uc001bvh.5; human. [Q9NW68-1]
DR CTD; 55108; -.
DR GeneCards; BSDC1; -.
DR HGNC; HGNC:25501; BSDC1.
DR HPA; ENSG00000160058; Low tissue specificity.
DR MIM; 617518; gene.
DR neXtProt; NX_Q9NW68; -.
DR OpenTargets; ENSG00000160058; -.
DR PharmGKB; PA142672548; -.
DR VEuPathDB; HostDB:ENSG00000160058; -.
DR eggNOG; KOG2690; Eukaryota.
DR GeneTree; ENSGT00390000009361; -.
DR HOGENOM; CLU_053864_0_0_1; -.
DR InParanoid; Q9NW68; -.
DR OMA; PCANVKF; -.
DR OrthoDB; 787655at2759; -.
DR PhylomeDB; Q9NW68; -.
DR TreeFam; TF313210; -.
DR PathwayCommons; Q9NW68; -.
DR SignaLink; Q9NW68; -.
DR BioGRID-ORCS; 55108; 17 hits in 1082 CRISPR screens.
DR ChiTaRS; BSDC1; human.
DR GenomeRNAi; 55108; -.
DR Pharos; Q9NW68; Tdark.
DR PRO; PR:Q9NW68; -.
DR Proteomes; UP000005640; Chromosome 1.
DR RNAct; Q9NW68; protein.
DR Bgee; ENSG00000160058; Expressed in sural nerve and 210 other tissues.
DR ExpressionAtlas; Q9NW68; baseline and differential.
DR Genevisible; Q9NW68; HS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR Gene3D; 1.10.3970.10; -; 1.
DR InterPro; IPR005607; BSD_dom.
DR InterPro; IPR035925; BSD_dom_sf.
DR Pfam; PF03909; BSD; 1.
DR SMART; SM00751; BSD; 1.
DR SUPFAM; SSF140383; SSF140383; 1.
DR PROSITE; PS50858; BSD; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Phosphoprotein; Reference proteome.
FT CHAIN 1..430
FT /note="BSD domain-containing protein 1"
FT /id="PRO_0000282639"
FT DOMAIN 146..198
FT /note="BSD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00036"
FT REGION 247..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 92
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:20068231"
FT MOD_RES 166
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:23186163"
FT MOD_RES 356
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:23186163"
FT MOD_RES 387
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:23186163,
FT ECO:0007744|PubMed:24275569"
FT MOD_RES 388
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:23186163"
FT MOD_RES 418
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:20068231"
FT VAR_SEQ 1..359
FT /note="Missing (in isoform 6)"
FT /evidence="ECO:0000303|PubMed:12975309"
FT /id="VSP_024216"
FT VAR_SEQ 1..104
FT /note="Missing (in isoform 4)"
FT /evidence="ECO:0000303|PubMed:14702039,
FT ECO:0000303|PubMed:17974005"
FT /id="VSP_024217"
FT VAR_SEQ 25..119
FT /note="Missing (in isoform 9)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_041672"
FT VAR_SEQ 63
FT /note="A -> AIAACSRGACFLCPFSIQ (in isoform 3 and isoform
FT 7)"
FT /evidence="ECO:0000303|PubMed:14702039,
FT ECO:0000303|PubMed:17974005"
FT /id="VSP_024218"
FT VAR_SEQ 64..120
FT /note="TEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPY
FT DGTKA -> A (in isoform 8)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_041673"
FT VAR_SEQ 146..173
FT /note="WLSQFCLEEKKGEISELLVGSPSIRALY -> CQPELWAQILVAPCWPSWAS
FT AHTWEGAL (in isoform 5)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_024219"
FT VAR_SEQ 174..430
FT /note="Missing (in isoform 5)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_024220"
FT VAR_SEQ 360..385
FT /note="EAPTDLRVFELNSDSGKSTPSNNGKK -> MLSPQLHPLQVPLPCLLLLFTL
FT WLVVP (in isoform 6)"
FT /evidence="ECO:0000303|PubMed:12975309"
FT /id="VSP_024221"
FT VAR_SEQ 386
FT /note="G -> ETRSQFTVDFLWKISVTLLEPLGQSASPLFSNLPFPRLKHGHQ (in
FT isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_024222"
FT VAR_SEQ 387..430
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_024223"
FT VAR_SEQ 421..430
FT /note="LEDVEWEDWE -> VSGPGGSEGSEPNGPGCESSPQPAQLSPQEGPCSCLR
FT (in isoform 3, isoform 4 and isoform 6)"
FT /evidence="ECO:0000303|PubMed:12975309,
FT ECO:0000303|PubMed:14702039, ECO:0000303|PubMed:17974005"
FT /id="VSP_024224"
FT CONFLICT 128
FT /note="D -> G (in Ref. 4; CAH18084)"
FT /evidence="ECO:0000305"
FT CONFLICT 137
FT /note="D -> G (in Ref. 7; AAH26322)"
FT /evidence="ECO:0000305"
FT CONFLICT 143
FT /note="F -> L (in Ref. 2; BAB13825)"
FT /evidence="ECO:0000305"
FT CONFLICT 149
FT /note="Q -> K (in Ref. 7; AAH26322)"
FT /evidence="ECO:0000305"
FT CONFLICT 250
FT /note="P -> H (in Ref. 7; AAH26322)"
FT /evidence="ECO:0000305"
FT CONFLICT 287
FT /note="T -> A (in Ref. 7; AAH26322)"
FT /evidence="ECO:0000305"
FT CONFLICT 430
FT /note="E -> D (in Ref. 3; CAG33533)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 430 AA; 47163 MW; 4031A3DC18A33646 CRC64;
MAEGEDVGWW RSWLQQSYQA VKEKSSEALE FMKRDLTEFT QVVQHDTACT IAATASVVKE
KLATEGSSGA TEKMKKGLSD FLGVISDTFA PSPDKTIDCD VITLMGTPSG TAEPYDGTKA
RLYSLQSDPA TYCNEPDGPP ELFDAWLSQF CLEEKKGEIS ELLVGSPSIR ALYTKMVPAA
VSHSEFWHRY FYKVHQLEQE QARRDALKQR AEQSISEEPG WEEEEEELMG ISPISPKEAK
VPVAKISTFP EGEPGPQSPC EENLVTSVEP PAEVTPSESS ESISLVTQIA NPATAPEARV
LPKDLSQKLL EASLEEQGLA VDVGETGPSP PIHSKPLTPA GHTGGPEPRP PARVETLREE
APTDLRVFEL NSDSGKSTPS NNGKKGSSTD ISEDWEKDFD LDMTEEEVQM ALSKVDASGE
LEDVEWEDWE
