BSHC_BACAC
ID BSHC_BACAC Reviewed; 538 AA.
AC C3L6F2;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Putative cysteine ligase BshC {ECO:0000255|HAMAP-Rule:MF_01867};
DE EC=6.-.-.- {ECO:0000255|HAMAP-Rule:MF_01867};
GN Name=bshC {ECO:0000255|HAMAP-Rule:MF_01867}; OrderedLocusNames=BAMEG_0569;
OS Bacillus anthracis (strain CDC 684 / NRRL 3495).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=568206;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 684 / NRRL 3495;
RA Dodson R.J., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C.,
RA Sutton G., Sims D.;
RT "Genome sequence of Bacillus anthracis str. CDC 684.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in bacillithiol (BSH) biosynthesis. May catalyze the
CC last step of the pathway, the addition of cysteine to glucosamine
CC malate (GlcN-Mal) to generate BSH. {ECO:0000255|HAMAP-Rule:MF_01867}.
CC -!- SIMILARITY: Belongs to the BshC family. {ECO:0000255|HAMAP-
CC Rule:MF_01867}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001215; ACP14896.1; -; Genomic_DNA.
DR RefSeq; WP_000403057.1; NC_012581.1.
DR AlphaFoldDB; C3L6F2; -.
DR SMR; C3L6F2; -.
DR GeneID; 45023748; -.
DR KEGG; bah:BAMEG_0569; -.
DR HOGENOM; CLU_022249_1_0_9; -.
DR OMA; TTGHQLN; -.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01867; BshC; 1.
DR InterPro; IPR011199; Bacillithiol_biosynth_BshC.
DR Pfam; PF10079; BshC; 1.
DR PIRSF; PIRSF012535; UCP012535; 1.
DR TIGRFAMs; TIGR03998; thiol_BshC; 1.
PE 3: Inferred from homology;
KW Coiled coil; Ligase.
FT CHAIN 1..538
FT /note="Putative cysteine ligase BshC"
FT /id="PRO_1000188715"
FT COILED 460..484
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01867"
SQ SEQUENCE 538 AA; 62974 MW; 9D5C31E2796D6590 CRC64;
MEIKEISVPQ QGVVADYMNG KKEIQSCFDY MLTEDAFKQR VQDLREREFF RQDLVTHLLE
YNTKLQAGEA TIQNVKALGD ENTYVVIAGQ QAGLLTGPLY TIHKIISVLQ LAKEKEESLG
VKVVPVFWIA GEDHDMDEIN HTFVTKNKKI KKTIFHDRNP KKASASESEL SLEDCRKWIE
EIFKTYPETN FTKDVLQFID DSLRKSNTYV DFFGHLIMKM FVNSGLILVD SHHPELRKLE
VPFFKQIVSK YKEVQEGLHN QQRVIKELGY KPIIETKSNA VHIFMEIDNE RVLLEDNQGK
FVGKDGTYSF SYKELIEEME RSPERFSNNV VTRPLMQEYV FPTLAFIGGP GELAYWSELQ
QVFHTIGFRM PPVVPRITIT YIERDIATDL HDLQLQESDP FFNNVDKLRE NWLSNQIEEP
IDERFVEAKK EIIDIHKSLQ QFVKKIDPGL SAFAGKNEFK INEQIELLER MLKRNVEKKH
EVELNKFRRI QFALRPLGAP QERVWNVCYY LNQFGLDFVD RVMEKPFSWN GKHHVIKL