ID   BSHC_BACC2              Reviewed;         538 AA.
AC   B7IVF4;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Putative cysteine ligase BshC {ECO:0000255|HAMAP-Rule:MF_01867};
DE            EC=6.-.-.- {ECO:0000255|HAMAP-Rule:MF_01867};
GN   Name=bshC {ECO:0000255|HAMAP-Rule:MF_01867};
GN   OrderedLocusNames=BCG9842_B1221;
OS   Bacillus cereus (strain G9842).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405531;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G9842;
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA   Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus G9842.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in bacillithiol (BSH) biosynthesis. May catalyze the
CC       last step of the pathway, the addition of cysteine to glucosamine
CC       malate (GlcN-Mal) to generate BSH. {ECO:0000255|HAMAP-Rule:MF_01867}.
CC   -!- SIMILARITY: Belongs to the BshC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01867}.
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DR   EMBL; CP001186; ACK98304.1; -; Genomic_DNA.
DR   RefSeq; WP_000403044.1; NC_011772.1.
DR   AlphaFoldDB; B7IVF4; -.
DR   SMR; B7IVF4; -.
DR   EnsemblBacteria; ACK98304; ACK98304; BCG9842_B1221.
DR   KEGG; bcg:BCG9842_B1221; -.
DR   HOGENOM; CLU_022249_1_0_9; -.
DR   OMA; TTGHQLN; -.
DR   Proteomes; UP000006744; Chromosome.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01867; BshC; 1.
DR   InterPro; IPR011199; Bacillithiol_biosynth_BshC.
DR   Pfam; PF10079; BshC; 1.
DR   PIRSF; PIRSF012535; UCP012535; 1.
DR   TIGRFAMs; TIGR03998; thiol_BshC; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Ligase.
FT   CHAIN           1..538
FT                   /note="Putative cysteine ligase BshC"
FT                   /id="PRO_0000378213"
FT   COILED          248..268
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01867"
SQ   SEQUENCE   538 AA;  62727 MW;  C140C93D7D70BA9A CRC64;
     MEIKEISVPQ QGVVADYMNG KKEIQSCFDY MLTEDAFKQR LHDLREREFF RQDVVAHLLE
     YNTKLQAGES TLQNVKALGD ENTYVVIAGQ QAGLLTGPLY TIHKVISILK LAKEKEESLG
     VKVVPVFWIA GEDHDMDEIN HTFLAKNKKM KKTIFYDRNP KKASASESEL SVEDCRNWIE
     EIFKTYPETN FTKDVLKFVD DALEKSNTYV DFFAHLITKI FANSGLILVD SHHPELRKLE
     IPFFKRIISK YKEVQEGLRN QQEVIKELGY KPIIETKSHA VHIFMEIDNE RVLLEEHQGK
     FVGKDGAHSF SYEELIEEME RNPARFSNNV VTRPLMQEYV FPTLAFIGGP GELAYWSELQ
     QVFHTVGFQM PPVVPRLTIT YVERCIATDL FDLQLRESDP FLNDVDKLRE NWLSNQIEEP
     IDNHFEKAKK EIADIHTSLQ QFVKKIEPGL SAFAGKNELK INEQIELLER MLKRNVEKKY
     EVQLNKFRRI QFALRPLGAP QERVWNVCYY LNQFGLDFVD RVMENPFSWD GKHHVIKL