ID   BSHC_BACCQ              Reviewed;         538 AA.
AC   B9IVZ6;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Putative cysteine ligase BshC {ECO:0000255|HAMAP-Rule:MF_01867};
DE            EC=6.-.-.- {ECO:0000255|HAMAP-Rule:MF_01867};
GN   Name=bshC {ECO:0000255|HAMAP-Rule:MF_01867}; OrderedLocusNames=BCQ_3705;
OS   Bacillus cereus (strain Q1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=361100;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Q1;
RX   PubMed=19060151; DOI=10.1128/jb.01629-08;
RA   Xiong Z., Jiang Y., Qi D., Lu H., Yang F., Yang J., Chen L., Sun L., Xu X.,
RA   Xue Y., Zhu Y., Jin Q.;
RT   "Complete genome sequence of the extremophilic Bacillus cereus strain Q1
RT   with industrial applications.";
RL   J. Bacteriol. 191:1120-1121(2009).
CC   -!- FUNCTION: Involved in bacillithiol (BSH) biosynthesis. May catalyze the
CC       last step of the pathway, the addition of cysteine to glucosamine
CC       malate (GlcN-Mal) to generate BSH. {ECO:0000255|HAMAP-Rule:MF_01867}.
CC   -!- SIMILARITY: Belongs to the BshC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01867}.
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DR   EMBL; CP000227; ACM14133.1; -; Genomic_DNA.
DR   RefSeq; WP_000403033.1; NC_011969.1.
DR   AlphaFoldDB; B9IVZ6; -.
DR   SMR; B9IVZ6; -.
DR   EnsemblBacteria; ACM14133; ACM14133; BCQ_3705.
DR   KEGG; bcq:BCQ_3705; -.
DR   HOGENOM; CLU_022249_1_0_9; -.
DR   OMA; TTGHQLN; -.
DR   Proteomes; UP000000441; Chromosome.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01867; BshC; 1.
DR   InterPro; IPR011199; Bacillithiol_biosynth_BshC.
DR   Pfam; PF10079; BshC; 1.
DR   PIRSF; PIRSF012535; UCP012535; 1.
DR   TIGRFAMs; TIGR03998; thiol_BshC; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Ligase.
FT   CHAIN           1..538
FT                   /note="Putative cysteine ligase BshC"
FT                   /id="PRO_0000378214"
FT   COILED          460..485
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01867"
SQ   SEQUENCE   538 AA;  62931 MW;  CF1AFAEE2A7C6898 CRC64;
     MEIKEISVPQ QGVVADYMNG EKEIQSCFDY MLTEDAFKQR VQDLREREFF RQDLVAHLLE
     YNTKLQAGEA TIQNVKALED EDTYVVIAGQ QAGLLTGPLY TIHKIISVLQ LAKEKEESLG
     VKVVPVFWIA GEDHDMDEIN HTFVTKNKKI KKTIFHDRNP KKASASESEL SLEDCRKWIE
     EIFKTYPETN FTKDVLRFID DSLGKSNTYV DFFGHLIMKM FINSGLILVD SHHPELRKLE
     VPFFKQIVSK YKEVQEGLHN QQEVIKELGY KPIIETKSNA VHIFMEIDNE RVLLEDNQGK
     FVGKDGTYSF SYEELIEEME RSPERFSNNV VTRPLMQEYV FPTLAFIGGP GELAYWSELQ
     QVFHTIGFRM PPVVPRITIT YIERDIATDL HDLQLQESDP FLNNVDKLRE NWLSNQIEEP
     IDERFVEAKK EIIDIHKSLQ QFVKKIDPGL SSFAGKNEFK INEQIELLER MLKRNIEKKH
     EVELNKFRRI QFAIRPLGAP QERVWNVCYY LNQFGLDFVD RVMEKPFSWN GKHHVIKL