ID   TIM16_DANRE             Reviewed;         129 AA.
AC   Q6PBL0;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit tim16;
DE   AltName: Full=Presequence translocated-associated motor subunit pam16;
GN   Name=pam16; Synonyms=tim16, timm16; ORFNames=zgc:73356;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulates ATP-dependent protein translocation into the
CC       mitochondrial matrix. {ECO:0000250}.
CC   -!- SUBUNIT: Probable component of the PAM complex at least composed of a
CC       mitochondrial HSP70 protein, GRPE, TIMM44, TIMM16/PAM16 and TIMM14.
CC       Associates with the TIM23 complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- DOMAIN: The J-like region, although related to the J domain does not
CC       have co-chaperone activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TIM16/PAM16 family. {ECO:0000305}.
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DR   EMBL; BC059670; AAH59670.1; -; mRNA.
DR   AlphaFoldDB; Q6PBL0; -.
DR   SMR; Q6PBL0; -.
DR   STRING; 7955.ENSDARP00000054355; -.
DR   PaxDb; Q6PBL0; -.
DR   ZFIN; ZDB-GENE-040426-1776; pam16.
DR   eggNOG; KOG3442; Eukaryota.
DR   InParanoid; Q6PBL0; -.
DR   PhylomeDB; Q6PBL0; -.
DR   PRO; PR:Q6PBL0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005744; C:TIM23 mitochondrial import inner membrane translocase complex; IBA:GO_Central.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR005341; Tim16.
DR   PANTHER; PTHR12388; PTHR12388; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Translocation; Transport.
FT   CHAIN           1..129
FT                   /note="Mitochondrial import inner membrane translocase
FT                   subunit tim16"
FT                   /id="PRO_0000214081"
FT   REGION          58..110
FT                   /note="J-like"
FT   REGION          110..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   129 AA;  14284 MW;  CE381F731EDFD847 CRC64;
     MAKYLAQIIV MGAQVVGRAF ARALRQEFAA SQAAAEARGQ AGRQSAAASS FTGMTLQEAQ
     QILNISTLTP EEIQKNYEHL FKVNDKAVGG SFYIQSKVVR AKERLDEELS INQQQQTKNK
     HADEQQQQT