ID   TIM17_DICDI             Reviewed;         183 AA.
AC   Q54K35;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit tim17;
GN   Name=timm17; Synonyms=tim17; ORFNames=DDB_G0287627;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May be involved in the translocation of transit peptide-
CC       containing proteins across the mitochondrial inner membrane.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Tim17/Tim22/Tim23 family. {ECO:0000305}.
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DR   EMBL; AAFI02000103; EAL63622.1; -; Genomic_DNA.
DR   RefSeq; XP_637129.1; XM_632037.1.
DR   AlphaFoldDB; Q54K35; -.
DR   SMR; Q54K35; -.
DR   STRING; 44689.DDB0238733; -.
DR   PaxDb; Q54K35; -.
DR   PRIDE; Q54K35; -.
DR   EnsemblProtists; EAL63622; EAL63622; DDB_G0287627.
DR   GeneID; 8626224; -.
DR   KEGG; ddi:DDB_G0287627; -.
DR   dictyBase; DDB_G0287627; timm17.
DR   eggNOG; KOG1652; Eukaryota.
DR   HOGENOM; CLU_087811_1_0_1; -.
DR   InParanoid; Q54K35; -.
DR   OMA; PWNAIAS; -.
DR   PhylomeDB; Q54K35; -.
DR   PRO; PR:Q54K35; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0005744; C:TIM23 mitochondrial import inner membrane translocase complex; IBA:GO_Central.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..183
FT                   /note="Mitochondrial import inner membrane translocase
FT                   subunit tim17"
FT                   /id="PRO_0000328273"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          131..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..183
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   183 AA;  20556 MW;  3F94B24F12797496 CRC64;
     MEAPCPDKIW QDAGGAFAIG YVLMGVVNIG LGFKRSPPNK RVLYTFALLR KKSPKFGGNF
     AIWGSLFSGF DCTLSYIRKT EDTVNPIAAG ALTGGILAAR SGWKHSVQAA AFGGIFIGII
     EAFQHMMQKR MQAQQEEMTQ QHLEERKRYE EERKQREGER KKLNENGKSK KNKQQQNGEN
     DLD