BSH_ARATH
ID BSH_ARATH Reviewed; 240 AA.
AC P93045; Q9LUN8;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Chromatin structure-remodeling complex protein BSH;
DE Short=AtBSH;
DE AltName: Full=Protein BUSHY;
DE AltName: Full=SNF5 homolog;
GN Name=BSH; OrderedLocusNames=At3g17590; ORFNames=MKP6.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF N-TERMINUS, FUNCTION,
RP SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Wassilewskija;
RX PubMed=10325430; DOI=10.1093/nar/27.11.2393;
RA Brzeski J., Podstolski W., Olczak K., Jerzmanowski A.;
RT "Identification and analysis of the Arabidopsis thaliana BSH gene, a member
RT of the SNF5 gene family.";
RL Nucleic Acids Res. 27:2393-2399(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP INTERACTION WITH BRM.
RX PubMed=15371304; DOI=10.1242/dev.01363;
RA Farrona S., Hurtado L., Bowman J.L., Reyes J.C.;
RT "The Arabidopsis thaliana SNF2 homolog AtBRM controls shoot development and
RT flowering.";
RL Development 131:4965-4975(2004).
RN [6]
RP INTERACTION WITH SWI3A AND SWI3B.
RX PubMed=16055636; DOI=10.1105/tpc.105.031203;
RA Sarnowski T.J., Rios G., Jasik J., Swiezewski S., Kaczanowski S., Li Y.,
RA Kwiatkowska A., Pawlikowska K., Kozbial M., Kozbial P., Koncz C.,
RA Jerzmanowski A.;
RT "SWI3 subunits of putative SWI/SNF chromatin-remodeling complexes play
RT distinct roles during Arabidopsis development.";
RL Plant Cell 17:2454-2472(2005).
CC -!- FUNCTION: Component of a multiprotein complex equivalent of the yeast
CC SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which
CC is required for the positive and negative regulation of gene expression
CC of a large number of genes. It changes chromatin structure by altering
CC DNA-histone contacts within a nucleosome, leading eventually to a
CC change in nucleosome position, thus facilitating or repressing binding
CC of gene-specific transcription factors. {ECO:0000269|PubMed:10325430}.
CC -!- SUBUNIT: Interacts with SWI3A and SWI3B, but not with BRM.
CC {ECO:0000269|PubMed:15371304, ECO:0000269|PubMed:16055636}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10325430}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=P93045-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and
CC siliques. {ECO:0000269|PubMed:10325430}.
CC -!- MISCELLANEOUS: Was named BUSHY by PubMed:10325430 because antisense
CC transgenic plants have a 'bushy' phenotype.
CC -!- SIMILARITY: Belongs to the SNF5 family. {ECO:0000305}.
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DR EMBL; U88061; AAB47766.1; -; mRNA.
DR EMBL; AB022219; BAB02049.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75971.1; -; Genomic_DNA.
DR EMBL; AK117162; BAC41840.1; -; mRNA.
DR RefSeq; NP_566581.1; NM_112639.4. [P93045-1]
DR AlphaFoldDB; P93045; -.
DR SMR; P93045; -.
DR BioGRID; 6358; 30.
DR IntAct; P93045; 2.
DR STRING; 3702.AT3G17590.2; -.
DR PaxDb; P93045; -.
DR PRIDE; P93045; -.
DR ProteomicsDB; 240504; -. [P93045-1]
DR EnsemblPlants; AT3G17590.1; AT3G17590.1; AT3G17590. [P93045-1]
DR GeneID; 821025; -.
DR Gramene; AT3G17590.1; AT3G17590.1; AT3G17590. [P93045-1]
DR KEGG; ath:AT3G17590; -.
DR Araport; AT3G17590; -.
DR eggNOG; KOG1649; Eukaryota.
DR HOGENOM; CLU_082256_0_0_1; -.
DR InParanoid; P93045; -.
DR PhylomeDB; P93045; -.
DR PRO; PR:P93045; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; P93045; baseline and differential.
DR GO; GO:0000228; C:nuclear chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0070603; C:SWI/SNF superfamily-type complex; IEA:UniProt.
DR GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR006939; SNF5.
DR Pfam; PF04855; SNF5; 2.
PE 1: Evidence at protein level;
KW Activator; Alternative splicing; Cell cycle; Chromatin regulator;
KW Direct protein sequencing; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..240
FT /note="Chromatin structure-remodeling complex protein BSH"
FT /id="PRO_0000205956"
FT CONFLICT 109
FT /note="H -> Q (in Ref. 1; AAB47766)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 240 AA; 27289 MW; C38055D92BC68CAA CRC64;
MKGLVSTGWK GPVKFRMPTA ENLVPIRLDI QFEGQRYKDA FTWNPSDPDN EVVIFAKRTV
KDLKLPYAFV TQIAQSIQSQ LSDFRAYEGQ DMYTGEKIIP IKLDLRVNHT LIKDQFLWDL
NNFESDPEEF ARTLCKDLGV EDPEVGPAVA FAIREQLYEI AIQSVASARE SRLSKKGRRG
SDHGSASKAS GLSMDLMKLF SFKSSVVRKR KDLDVYEPVV DLLTSEEVDA LEAREERHAR
