TIP43_MAIZE
ID TIP43_MAIZE Reviewed; 249 AA.
AC Q9ATL4;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Aquaporin TIP4-3;
DE AltName: Full=Tonoplast intrinsic protein 4-3;
DE AltName: Full=ZmTIP4-3;
DE AltName: Full=ZmTIP4;3;
GN Name=TIP4-3;
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. B73;
RX PubMed=11244102; DOI=10.1104/pp.125.3.1206;
RA Chaumont F., Barrieu F., Wojcik E., Chrispeels M.J., Jung R.;
RT "Aquaporins constitute a large and highly divergent protein family in
RT maize.";
RL Plant Physiol. 125:1206-1215(2001).
CC -!- FUNCTION: Aquaporins facilitate the transport of water and small
CC neutral solutes across cell membranes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}. Note=Tonoplast.
CC -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC membrane-spanning domains and a pore-forming loop with the signature
CC motif Asn-Pro-Ala (NPA).
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC
CC 1.A.8.10) subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF326507; AAK26774.1; -; mRNA.
DR RefSeq; NP_001105035.1; NM_001111565.1.
DR AlphaFoldDB; Q9ATL4; -.
DR SMR; Q9ATL4; -.
DR STRING; 4577.GRMZM2G146627_P01; -.
DR PaxDb; Q9ATL4; -.
DR eggNOG; KOG0223; Eukaryota.
DR Proteomes; UP000007305; Unplaced.
DR ExpressionAtlas; Q9ATL4; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; TAS:AgBase.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015250; F:water channel activity; IBA:GO_Central.
DR GO; GO:0006833; P:water transport; IBA:GO_Central.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR45665; PTHR45665; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix;
KW Transport; Vacuole.
FT CHAIN 1..249
FT /note="Aquaporin TIP4-3"
FT /id="PRO_0000286010"
FT TRANSMEM 20..40
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..122
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..161
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT MOTIF 82..84
FT /note="NPA 1"
FT /evidence="ECO:0000250"
FT MOTIF 195..197
FT /note="NPA 2"
FT /evidence="ECO:0000250"
SQ SEQUENCE 249 AA; 25259 MW; EF09E2F9920A390B CRC64;
MGKLTLGHRG EASEPDFFRG VLGELVLTFL FVFIGVGAAM TDGATTKGST AGGDLTAVAL
GQALVVAVIA TAGFHISGGH VNPAVTLSLA VGGHVTLFRS SLYIAAQMLA SSAACFLLRW
LTGGLATPVH ALAEGVGPLQ GVVAEAVFTF SLLFVIYATI LDPRKLLPGA GPLLTGLLVG
ANSVAGAALS GASMNPARSF GPAVASGVWT HHWVYWVGPL AGGPLAVLVY ECCFMAAAPT
HDLLPQQDP
