ID   TIQ2_RHISA              Reviewed;          31 AA.
AC   P84554;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Kunitz-type serine protease inhibitor RsTIQ2;
DE   Flags: Fragment;
OS   Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae;
OC   Rhipicephalus; Rhipicephalus.
OX   NCBI_TaxID=34632;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   TISSUE=Larva {ECO:0000269|PubMed:12941299};
RX   PubMed=12941299; DOI=10.1016/s0003-9861(03)00344-8;
RA   Sant'Anna Azzolini S., Sasaki S.D., Torquato R.J.S., Andreotti R.,
RA   Andreotti E., Tanaka A.S.;
RT   "Rhipicephalus sanguineus trypsin inhibitors present in the tick larvae:
RT   isolation, characterization, and partial primary structure determination.";
RL   Arch. Biochem. Biophys. 417:176-182(2003).
CC   -!- FUNCTION: Serine protease inhibitor. Inhibits trypsin, elastase,
CC       plasmin and kallikrein. {ECO:0000269|PubMed:12941299}.
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DR   AlphaFoldDB; P84554; -.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Protease inhibitor;
KW   Serine protease inhibitor.
FT   CHAIN           1..>31
FT                   /note="Kunitz-type serine protease inhibitor RsTIQ2"
FT                   /id="PRO_0000155459"
FT   DOMAIN          1..>31
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00031"
FT   SITE            19..20
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250|UniProtKB:P31713"
FT   DISULFID        9..?
FT                   /evidence="ECO:0000250|UniProtKB:P31713,
FT                   ECO:0000255|PROSITE-ProRule:PRU00031"
FT   DISULFID        18..?
FT                   /evidence="ECO:0000250|UniProtKB:P31713,
FT                   ECO:0000255|PROSITE-ProRule:PRU00031"
FT   NON_TER         31
FT                   /evidence="ECO:0000303|PubMed:12941299"
SQ   SEQUENCE   31 AA;  3557 MW;  76E1E164F8D12378 CRC64;
     EAVDFDSQCV PTADPGKCKF YFPMWNVNVF T