ID   TIQ7_RHISA              Reviewed;          29 AA.
AC   P84555;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Kunitz-type serine protease inhibitor RsTIQ7;
DE   Flags: Fragment;
OS   Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae;
OC   Rhipicephalus; Rhipicephalus.
OX   NCBI_TaxID=34632;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   TISSUE=Larva {ECO:0000269|PubMed:12941299};
RX   PubMed=12941299; DOI=10.1016/s0003-9861(03)00344-8;
RA   Sant'Anna Azzolini S., Sasaki S.D., Torquato R.J.S., Andreotti R.,
RA   Andreotti E., Tanaka A.S.;
RT   "Rhipicephalus sanguineus trypsin inhibitors present in the tick larvae:
RT   isolation, characterization, and partial primary structure determination.";
RL   Arch. Biochem. Biophys. 417:176-182(2003).
CC   -!- FUNCTION: Serine protease inhibitor. Inhibits trypsin, elastase,
CC       plasmin and kallikrein. {ECO:0000269|PubMed:12941299}.
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DR   AlphaFoldDB; P84555; -.
DR   SMR; P84555; -.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   InterPro; IPR036880; Kunitz_BPTI_sf.
DR   SUPFAM; SSF57362; SSF57362; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Protease inhibitor;
KW   Serine protease inhibitor.
FT   CHAIN           1..>29
FT                   /note="Kunitz-type serine protease inhibitor RsTIQ7"
FT                   /id="PRO_0000155460"
FT   DOMAIN          6..26
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00031"
FT   SITE            17..18
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000250|UniProtKB:P31713"
FT   DISULFID        7..?
FT                   /evidence="ECO:0000250|UniProtKB:P31713,
FT                   ECO:0000255|PROSITE-ProRule:PRU00031"
FT   DISULFID        16..?
FT                   /evidence="ECO:0000250|UniProtKB:P31713,
FT                   ECO:0000255|PROSITE-ProRule:PRU00031"
FT   NON_TER         29
FT                   /evidence="ECO:0000303|PubMed:12941299"
SQ   SEQUENCE   29 AA;  3334 MW;  6E83F262382278CA CRC64;
     EDFDSQCVPT ADPGPCKAYI PMWWYNVLS