ID   TKB1_STRPU              Reviewed;         400 AA.
AC   Q26648;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Tektin-B1;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 207-245; 289-334 AND
RP   380-400.
RC   TISSUE=Blastula;
RX   PubMed=8308073; DOI=10.1242/jcs.106.3.909;
RA   Chen R., Perrone C.A., Amos L.A., Linck R.W.;
RT   "Tektin B1 from ciliary microtubules: primary structure as deduced from the
RT   cDNA sequence and comparison with tektin A1.";
RL   J. Cell Sci. 106:909-918(1993).
CC   -!- FUNCTION: Structural component of ciliary and flagellar microtubules.
CC   -!- SUBUNIT: May form a heterodimer with tektin a or exist as a homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton.
CC       Note=Microtubule-associated.
CC   -!- TISSUE SPECIFICITY: Cilia and flagella.
CC   -!- SIMILARITY: Belongs to the tektin family. {ECO:0000305}.
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DR   EMBL; L21838; AAA19672.1; -; mRNA.
DR   RefSeq; NP_999789.1; NM_214624.1.
DR   AlphaFoldDB; Q26648; -.
DR   SMR; Q26648; -.
DR   STRING; 7668.SPU_020728-tr; -.
DR   EnsemblMetazoa; NM_214624; NP_999789; LOC373482.
DR   GeneID; 373482; -.
DR   KEGG; spu:373482; -.
DR   eggNOG; KOG2685; Eukaryota.
DR   HOGENOM; CLU_033588_0_0_1; -.
DR   OrthoDB; 581072at2759; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR   GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IBA:GO_Central.
DR   InterPro; IPR000435; Tektin.
DR   PANTHER; PTHR19960; PTHR19960; 1.
DR   PRINTS; PR00511; TEKTIN.
PE   1: Evidence at protein level;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Direct protein sequencing;
KW   Microtubule; Reference proteome.
FT   CHAIN           1..400
FT                   /note="Tektin-B1"
FT                   /id="PRO_0000184570"
FT   COILED          35..81
FT                   /evidence="ECO:0000255"
FT   COILED          236..294
FT                   /evidence="ECO:0000255"
FT   COILED          310..353
FT                   /evidence="ECO:0000255"
FT   CONFLICT        245
FT                   /note="M -> T (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        330
FT                   /note="Q -> F (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        332..333
FT                   /note="AH -> FF (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        335
FT                   /note="A -> F (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   400 AA;  46148 MW;  1E8BD51A5920D9A0 CRC64;
     MLRNSVITPT PPAKNLASFV TKPTTDIMGY HDNTTRLSNR IDDIETWRET LEKTLADVDE
     EIRKLEEDKD LAERALEAKA LPLDVASECK TLRDGRRDND VVDDLANSEV GKEIDVIEGI
     KDALQAKVSS AFEQLCLLQE ARQQLHADLR DKTEAKKIDT YCHDLTISSP DICYQPNSTR
     TPKGSTTPQT WEDFSRYNKD RADAEMRSSQ RLREAIHSTV AQTDNDLEAQ RQATEFALRK
     RIHEMKRAKD EDEWQKKNTE EEIAKQERNI RELEQAIKDK ENPLKLAMTR LENRTYRPNV
     ELCRDNAQYG LVNEVHEIQD SIKALEKKLQ DAHNARDACE KQLYRINKDL ELKNNSLDLD
     NKCMQVREKL TTGPVTQTMN NLSTFKTDRE LYTAQRSLLA