TKN1_SCHGR
ID TKN1_SCHGR Reviewed; 14 AA.
AC P82470;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 1.
DT 11-DEC-2019, entry version 44.
DE RecName: Full=Tachykinin-1;
DE AltName: Full=Scg-midgut-TK;
OS Schistocerca gregaria (Desert locust) (Gryllus gregarius).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC Acridoidea; Acrididae; Cyrtacanthacridinae; Schistocerca.
OX NCBI_TaxID=7010;
RN [1]
RP PROTEIN SEQUENCE, AMIDATION AT ARG-14, AND MASS SPECTROMETRY.
RC TISSUE=Midgut;
RX PubMed=10581195; DOI=10.1006/bbrc.1999.1808;
RA Veelaert D., Baggerman G., Derua R., Waelkens E., Meeusen T.,
RA Vande Water G., De Loof A., Schoofs L.;
RT "Identification of a new tachykinin from the midgut of the desert locust,
RT Schistocerca gregaria, by ESI-Qq-oa-TOF mass spectrometry.";
RL Biochem. Biophys. Res. Commun. 266:237-242(1999).
CC -!- FUNCTION: Myoactive peptide. Increases the amplitude and frequency of
CC spontaneous contractions and tonus of hindgut muscle.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Midgut.
CC -!- MASS SPECTROMETRY: Mass=1493.79; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:10581195};
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DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..14
FT /note="Tachykinin-1"
FT /id="PRO_0000044447"
FT MOD_RES 14
FT /note="Arginine amide"
FT /evidence="ECO:0000269|PubMed:10581195"
SQ SEQUENCE 14 AA; 1496 MW; CA4C578C0169FC72 CRC64;
GNTKKAVPGF YGTR