ID   TKN2_PHLMA              Reviewed;          12 AA.
AC   P08614;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   07-APR-2021, entry version 61.
DE   RecName: Full=Hylambatin;
OS   Phlyctimantis maculatus (Red-legged running frog) (Hylambates maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Microhyloidea; Hyperoliidae; Kassina.
OX   NCBI_TaxID=2517390;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT MET-12.
RC   TISSUE=Skin secretion;
RA   Yasuhara T., Nakajima T., Erspamer G.F., Erspamer V.;
RT   "New tachykinins, Glu2, Pro5-kassinin (hylambates-kassinin) and hylambatin,
RT   in the skin of the African rhacophorid frog Hylambates maculatus.";
RL   Biomed. Res. 2:613-617(1981).
CC   -!- FUNCTION: Tachykinins are active peptides which excite neurons, evoke
CC       behavioral responses, are potent vasodilators and secretagogues, and
CC       contract (directly or indirectly) many smooth muscles.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC   -!- SIMILARITY: Belongs to the tachykinin family. {ECO:0000305}.
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DR   PIR; S07436; S07436.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR013055; Tachy_Neuro_lke_CS.
DR   PROSITE; PS00267; TACHYKININ; 1.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Direct protein sequencing;
KW   Neuropeptide; Secreted.
FT   PEPTIDE         1..12
FT                   /note="Hylambatin"
FT                   /id="PRO_0000044396"
FT   MOD_RES         12
FT                   /note="Methionine amide"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   12 AA;  1441 MW;  3287CD2F0DD40AB7 CRC64;
     DPPDPDRFYG MM