ID   TKN2_SCYCA              Reviewed;          18 AA.
AC   P08609;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Scyliorhinin-2;
DE   AltName: Full=Rectin;
DE   AltName: Full=Scyliorhinin II;
OS   Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=7830;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT MET-18.
RC   TISSUE=Intestine;
RX   PubMed=2422058; DOI=10.1016/0014-5793(86)80521-x;
RA   Conlon J.M., Deacon C.F., O'Toole L., Thim L.;
RT   "Scyliorhinin I and II: two novel tachykinins from dogfish gut.";
RL   FEBS Lett. 200:111-116(1986).
RN   [2]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Small intestine;
RX   PubMed=7541963; DOI=10.1152/ajpregu.1995.268.6.r1359;
RA   Anderson W.G., Conlon J.M., Hazon N.;
RT   "Characterization of the endogenous intestinal peptide that stimulates the
RT   rectal gland of Scyliorhinus canicula.";
RL   Am. J. Physiol. 268:R1359-R1364(1995).
CC   -!- FUNCTION: Tachykinins are active peptides which excite neurons, evoke
CC       behavioral responses, are potent vasodilators and secretagogues, and
CC       contract (directly or indirectly) many smooth muscles.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the tachykinin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; B24867; B24867.
DR   AlphaFoldDB; P08609; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR013055; Tachy_Neuro_lke_CS.
DR   PROSITE; PS00267; TACHYKININ; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Neuropeptide;
KW   Secreted.
FT   PEPTIDE         1..18
FT                   /note="Scyliorhinin-2"
FT                   /id="PRO_0000044411"
FT   MOD_RES         18
FT                   /note="Methionine amide"
FT                   /evidence="ECO:0000269|PubMed:2422058"
FT   DISULFID        7..13
SQ   SEQUENCE   18 AA;  1854 MW;  FCCA3FB01E2F3907 CRC64;
     SPSNSKCPDG PDCFVGLM