ID   TKNA_PELRI              Reviewed;          11 AA.
AC   P29207;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   11-DEC-2019, entry version 60.
DE   RecName: Full=Ranakinin;
DE   AltName: Full=Substance-P-related peptide;
OS   Pelophylax ridibundus (Marsh frog) (Rana ridibunda).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Pelophylax.
OX   NCBI_TaxID=8406;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT MET-11.
RC   TISSUE=Brain;
RX   PubMed=1658233; DOI=10.1111/j.1471-4159.1991.tb06426.x;
RA   O'Harte F., Burcher E., Lovas S., Smith D.D., Vaudry H., Conlon J.M.;
RT   "Ranakinin: a novel NK1 tachykinin receptor agonist isolated with
RT   neurokinin B from the brain of the frog Rana ridibunda.";
RL   J. Neurochem. 57:2086-2091(1991).
CC   -!- FUNCTION: Tachykinins are active peptides which excite neurons, evoke
CC       behavioral responses, are potent vasodilators and secretagogues, and
CC       contract (directly or indirectly) many smooth muscles.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the tachykinin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; IEA:InterPro.
DR   InterPro; IPR013055; Tachy_Neuro_lke_CS.
DR   InterPro; IPR008215; Tachykinin_dom.
DR   Pfam; PF02202; Tachykinin; 1.
DR   PROSITE; PS00267; TACHYKININ; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..11
FT                   /note="Ranakinin"
FT                   /id="PRO_0000044417"
FT   MOD_RES         11
FT                   /note="Methionine amide"
FT                   /evidence="ECO:0000269|PubMed:1658233"
SQ   SEQUENCE   11 AA;  1352 MW;  3A2460CC59D40B07 CRC64;
     KPNPERFYGL M