ID   TKNB_CHICK              Reviewed;          10 AA.
AC   P19851;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   02-JUN-2021, entry version 78.
DE   RecName: Full=Neurokinin-A;
DE   AltName: Full=Neuromedin-L;
DE   AltName: Full=Substance K;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT MET-10.
RC   TISSUE=Intestine;
RX   PubMed=2452461; DOI=10.1016/0167-0115(88)90050-x;
RA   Conlon J.M., Katsoulis S., Schmidt W.E., Thim L.;
RT   "[Arg3]substance P and neurokinin A from chicken small intestine.";
RL   Regul. Pept. 20:171-180(1988).
CC   -!- FUNCTION: Tachykinins are active peptides which excite neurons, evoke
CC       behavioral responses, are potent vasodilators and secretagogues, and
CC       contract (directly or indirectly) many smooth muscles.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the tachykinin family. {ECO:0000305}.
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DR   PIR; JN0024; JN0024.
DR   PDB; 1N6T; NMR; -; A=1-10.
DR   PDBsum; 1N6T; -.
DR   BMRB; P19851; -.
DR   SMR; P19851; -.
DR   EvolutionaryTrace; P19851; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR013055; Tachy_Neuro_lke_CS.
DR   PROSITE; PS00267; TACHYKININ; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Amidation; Direct protein sequencing; Neuropeptide;
KW   Reference proteome; Secreted.
FT   PEPTIDE         1..10
FT                   /note="Neurokinin-A"
FT                   /id="PRO_0000044425"
FT   MOD_RES         10
FT                   /note="Methionine amide"
FT                   /evidence="ECO:0000269|PubMed:2452461"
FT   HELIX           4..9
FT                   /evidence="ECO:0007829|PDB:1N6T"
SQ   SEQUENCE   10 AA;  1134 MW;  8A6B4062C9D5BAB1 CRC64;
     HKTDSFVGLM