TKNB_LITCT
ID TKNB_LITCT Reviewed; 10 AA.
AC P22689;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 26-FEB-2020, entry version 56.
DE RecName: Full=Ranatachykinin-B;
DE Short=RTK B;
OS Lithobates catesbeianus (American bullfrog) (Rana catesbeiana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Lithobates.
OX NCBI_TaxID=8400;
RN [1]
RP PROTEIN SEQUENCE, SYNTHESIS, AND AMIDATION AT MET-10.
RC TISSUE=Brain;
RX PubMed=2043143; DOI=10.1016/0006-291x(91)92024-e;
RA Kozawa H., Hino J., Minamino N., Kangawa K., Matsuo H.;
RT "Isolation of four novel tachykinins from frog (Rana catesbeiana) brain and
RT intestine.";
RL Biochem. Biophys. Res. Commun. 177:588-595(1991).
RN [2]
RP PROTEIN SEQUENCE.
RC TISSUE=Intestine;
RX PubMed=8210506; DOI=10.1016/0167-0115(93)90016-2;
RA Kangawa K., Kozawa H., Hino J., Minamino N., Matsuo H.;
RT "Four novel tachykinins in frog (Rana catesbeiana) brain and intestine.";
RL Regul. Pept. 46:81-88(1993).
CC -!- FUNCTION: Tachykinins are active peptides which excite neurons, evoke
CC behavioral responses, are potent vasodilators and secretagogues, and
CC contract (directly or indirectly) many smooth muscles.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the tachykinin family. {ECO:0000305}.
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DR PIR; B61033; B61033.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR013055; Tachy_Neuro_lke_CS.
DR PROSITE; PS00267; TACHYKININ; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..10
FT /note="Ranatachykinin-B"
FT /id="PRO_0000044406"
FT MOD_RES 10
FT /note="Methionine amide"
FT /evidence="ECO:0000269|PubMed:2043143"
SQ SEQUENCE 10 AA; 1210 MW; 917E556B59D5BAB5 CRC64;
YKSDSFYGLM