TKND_LITCT
ID TKND_LITCT Reviewed; 11 AA.
AC P22691;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 26-FEB-2020, entry version 57.
DE RecName: Full=Ranatachykinin-D;
DE Short=RTK D;
OS Lithobates catesbeianus (American bullfrog) (Rana catesbeiana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Lithobates.
OX NCBI_TaxID=8400;
RN [1]
RP PROTEIN SEQUENCE, SYNTHESIS, AND AMIDATION AT MET-11.
RC TISSUE=Intestine;
RX PubMed=2043143; DOI=10.1016/0006-291x(91)92024-e;
RA Kozawa H., Hino J., Minamino N., Kangawa K., Matsuo H.;
RT "Isolation of four novel tachykinins from frog (Rana catesbeiana) brain and
RT intestine.";
RL Biochem. Biophys. Res. Commun. 177:588-595(1991).
RN [2]
RP PROTEIN SEQUENCE.
RC TISSUE=Intestine;
RX PubMed=8210506; DOI=10.1016/0167-0115(93)90016-2;
RA Kangawa K., Kozawa H., Hino J., Minamino N., Matsuo H.;
RT "Four novel tachykinins in frog (Rana catesbeiana) brain and intestine.";
RL Regul. Pept. 46:81-88(1993).
CC -!- FUNCTION: Tachykinins are active peptides which excite neurons, evoke
CC behavioral responses, are potent vasodilators and secretagogues, and
CC contract (directly or indirectly) many smooth muscles.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the tachykinin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR PIR; D61033; D61033.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..11
FT /note="Ranatachykinin-D"
FT /id="PRO_0000044408"
FT MOD_RES 11
FT /note="Methionine amide"
FT /evidence="ECO:0000269|PubMed:2043143"
SQ SEQUENCE 11 AA; 1350 MW; 3A34256C59D40B07 CRC64;
KPNPERFYAP M