TKTI1_MACFA
ID TKTI1_MACFA Reviewed; 209 AA.
AC A5LFW8;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 21.
DE RecName: Full=Tektin bundle interacting protein 1;
GN Name=TEKTIP1; ORFNames=QtsA-14935;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG International consortium for macaque cDNA sequencing and analysis;
RT "DNA sequences of macaque genes expressed in brain or testis and its
RT evolutionary implications.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia axoneme, which is required for
CC motile cilia beating. Located at the center of the tektin bundle where
CC may function to recruit tektins or stabilize the bundle.
CC {ECO:0000250|UniProtKB:Q2M2T2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000250|UniProtKB:Q2M2T2}.
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DR EMBL; AB168801; BAF63653.1; -; mRNA.
DR RefSeq; NP_001272172.1; NM_001285243.1.
DR AlphaFoldDB; A5LFW8; -.
DR STRING; 9541.XP_005587569.1; -.
DR GeneID; 101925355; -.
DR CTD; 100128569; -.
DR eggNOG; ENOG502S0K8; Eukaryota.
DR OrthoDB; 1400323at2759; -.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR InterPro; IPR029203; DUF4531.
DR PANTHER; PTHR31254; PTHR31254; 1.
DR Pfam; PF15041; DUF4531; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..209
FT /note="Tektin bundle interacting protein 1"
FT /id="PRO_0000332196"
SQ SEQUENCE 209 AA; 24402 MW; E0820398F77CA8B6 CRC64;
MQTLRREAAR PYVPSGTLEA SFPAPLYSDD YLSLEGPRWP LVIRQATRWK YTPMGRDAAG
QLWYTGLTNS DTREAWYNLP LDPASPFREA YNRWHGCYQR REHTMPSAYT QHLRETAWHD
PIIPAQYQVP STRWGSTLWK DRPIRGKEYV INRNRYGVEP LWRASDYVPS LSAPQRPPGT
TQNYREWGLE PYCPSTCQRP LPSSTPMPR