TLC1_CHLPN
ID TLC1_CHLPN Reviewed; 515 AA.
AC Q9Z8J2; Q9JSF8;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 121.
DE RecName: Full=ADP,ATP carrier protein 1;
DE AltName: Full=ADP/ATP translocase 1;
GN Name=tlcA; Synonyms=adt_1; OrderedLocusNames=CPn_0351, CP_0408, CpB0359;
OS Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=83558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC {ECO:0000305}.
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DR EMBL; AE001363; AAD18495.1; -; Genomic_DNA.
DR EMBL; AE002161; AAF38252.1; -; Genomic_DNA.
DR EMBL; BA000008; BAA98559.1; -; Genomic_DNA.
DR EMBL; AE009440; AAP98290.1; -; Genomic_DNA.
DR PIR; E72089; E72089.
DR PIR; E86534; E86534.
DR RefSeq; NP_224551.1; NC_000922.1.
DR RefSeq; WP_010882994.1; NZ_LN847257.1.
DR AlphaFoldDB; Q9Z8J2; -.
DR STRING; 115711.CP_0408; -.
DR EnsemblBacteria; AAD18495; AAD18495; CPn_0351.
DR EnsemblBacteria; AAF38252; AAF38252; CP_0408.
DR GeneID; 45050397; -.
DR KEGG; cpa:CP_0408; -.
DR KEGG; cpj:adt_1; -.
DR KEGG; cpn:CPn_0351; -.
DR KEGG; cpt:CpB0359; -.
DR PATRIC; fig|115713.3.peg.388; -.
DR eggNOG; COG3202; Bacteria.
DR HOGENOM; CLU_023964_0_1_0; -.
DR OrthoDB; 427341at2; -.
DR Proteomes; UP000000583; Chromosome.
DR Proteomes; UP000000801; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR InterPro; IPR004667; ADP_ATP_car_bac_type.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31187; PTHR31187; 1.
DR Pfam; PF03219; TLC; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00769; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..515
FT /note="ADP,ATP carrier protein 1"
FT /id="PRO_0000102586"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 465..485
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 141
FT /note="V -> D (in Ref. 3; BAA98559)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 515 AA; 57197 MW; F3F4A52CE008E106 CRC64;
MTKTEEKPFG KLRSFLWPIH THELKKVLPM FLMFFCITFN YTVLRDTKDT LIVGAPGSGA
EAIPFIKFWL VVPCAIIFML IYAKLSNILS KQALFYAVGT PFLIFFALFP TVIYPLRDVL
HPTEFADRLQ AILPPGLLGL VAILRNWTFA AFYVLAELWG SVMLSLMFWG FANEITKIHE
AKRFYALFGI GANISLLASG RAIVWASKLR ASVSEGVDPW GISLRLLMAM TIVSGLVLMA
SYWWINKNVL TDPRFYNPEE MQKGKKGAKP KMNMKDSFLY LARSPYILLL ALLVIAYGIC
INLIEVTWKS QLKLQYPNMN DYSEFMGNFS FWTGVVSVLI MLFVGGNVIR KFGWLTGALV
TPVMVLLTGI VFFALVIFRN QASGLVAMFG TTPLMLAVVV GAIQNILSKS TKYALFDSTK
EMAYIPLDQE QKVKGKAAID VVAARFGKSG GALIQQGLLV ICGSIGAMTP YLAVILLFII
AIWLVSATKL NKLFLAQSAL KEQEVAQEDS APASS
