TLC2_CHLPN
ID TLC2_CHLPN Reviewed; 540 AA.
AC Q9Z7U0; Q9JQI0;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=ADP,ATP carrier protein 2;
DE AltName: Full=ADP/ATP translocase 2;
GN Name=tlcB; Synonyms=adt_2; OrderedLocusNames=CPn_0614, CP_0133, CpB0638;
OS Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=83558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC {ECO:0000305}.
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DR EMBL; AE001363; AAD18753.1; -; Genomic_DNA.
DR EMBL; AE002161; AAF38016.1; -; Genomic_DNA.
DR EMBL; BA000008; BAA98821.1; -; Genomic_DNA.
DR EMBL; AE009440; AAP98567.1; -; Genomic_DNA.
DR PIR; B72056; B72056.
DR PIR; C86567; C86567.
DR RefSeq; NP_224810.1; NC_000922.1.
DR RefSeq; WP_010883252.1; NZ_LN847257.1.
DR AlphaFoldDB; Q9Z7U0; -.
DR STRING; 115711.CP_0133; -.
DR EnsemblBacteria; AAD18753; AAD18753; CPn_0614.
DR EnsemblBacteria; AAF38016; AAF38016; CP_0133.
DR GeneID; 45050662; -.
DR KEGG; cpa:CP_0133; -.
DR KEGG; cpj:adt_2; -.
DR KEGG; cpn:CPn_0614; -.
DR KEGG; cpt:CpB0638; -.
DR PATRIC; fig|115713.3.peg.683; -.
DR eggNOG; COG3202; Bacteria.
DR HOGENOM; CLU_023964_0_1_0; -.
DR OrthoDB; 427341at2; -.
DR Proteomes; UP000000583; Chromosome.
DR Proteomes; UP000000801; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR004667; ADP_ATP_car_bac_type.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31187; PTHR31187; 1.
DR Pfam; PF03219; TLC; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00769; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..540
FT /note="ADP,ATP carrier protein 2"
FT /id="PRO_0000102589"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 458..478
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 480..500
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 540 AA; 60050 MW; 57A6023AE02FABA3 CRC64;
MQSSEVKPFS RLRAYLCPIY KSEFSKFVPL FLLAFFVGFN YCLLKNMKDT LVIVGSDAGA
EVIPFLKVWG IVPGAVIVTM VYGWLGSRYP RDTVFYCFMA AFLGFFFLFA VIIYPVGDSL
HLNSLADKLQ ELLPQGLRGF IVMVRYWSYS IYYVMSELWS SVVLSMLFWG LANQITTITE
AGRFYALINT GLNLSSICAG EISYWMGKQT FVAYSFACDS WHSVMLNLTM LITCSGLIMI
WLYRRIHHLT IDTSIPPSRR VLAEEGAATA NLKEKKKPKA KARNLFLHLI QSRYLLGLAI
IVLSYNLVIH LFEVVWKDQV SQIYSSHVEF NGYMSRITTL IGVVSVLAAV LLTGQCIRKW
GWTVGALVTP LVMLVSGLLF FGTIFAAKRD ISIFGGVLGM TPLALAAWTG GMQNVLSRGT
KFTFFDQTKE MAFIPLSPED KNHGKAAIDG VVSRIGKSGG SLIYQGLLVI FSSVAASLNV
IALVLLIIMV VWIAVVAYIG KEYYSRAADA VATLKQPKEP SSSIVREAQE SVEQEEMAVL
