ID   TLCB_RICBR              Reviewed;         507 AA.
AC   Q1RHU3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=ADP,ATP carrier protein 2;
DE   AltName: Full=ADP/ATP translocase 2;
GN   Name=tlcB; Synonyms=tlc2; OrderedLocusNames=RBE_0990;
OS   Rickettsia bellii (strain RML369-C).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX   NCBI_TaxID=336407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RML369-C;
RX   PubMed=16703114; DOI=10.1371/journal.pgen.0020076;
RA   Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C.,
RA   Fournier P.-E., Claverie J.-M., Raoult D.;
RT   "Genome sequence of Rickettsia bellii illuminates the role of amoebae in
RT   gene exchanges between intracellular pathogens.";
RL   PLoS Genet. 2:733-744(2006).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; CP000087; ABE05071.1; -; Genomic_DNA.
DR   RefSeq; WP_011477651.1; NC_007940.1.
DR   AlphaFoldDB; Q1RHU3; -.
DR   STRING; 336407.RBE_0990; -.
DR   EnsemblBacteria; ABE05071; ABE05071; RBE_0990.
DR   KEGG; rbe:RBE_0990; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; HIVWPIR; -.
DR   OrthoDB; 427341at2; -.
DR   Proteomes; UP000001951; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..507
FT                   /note="ADP,ATP carrier protein 2"
FT                   /id="PRO_0000286482"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        333..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        451..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        474..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   507 AA;  58624 MW;  8EE461ED6506D2CC CRC64;
     MDAVNSNFTF WNRARNSKFR HIVWPIRSYE LTKFIPMALL MFFILLNQNL VRSIKDSFVV
     TLINTEVLSF IKLWGEMPMG VLFVILYSKL CNLMTTEQVF RIITSTFLLF FAFFGFVLFP
     YREFFHPDPE LVKHYITVLP HLKWFIIIWG QWSLVLFYIM GELWPVIVFT LLYWQLANKI
     TKVEEAPRFY SFFTLFGQTN LLISGTIIIY FAKSEHFLLP LFSHLSDTNE ILLKSFVSII
     LVSGLICLAL HKFIDKTVVE SDKNIKFKNQ RTDILKLSLI ESTKIILTSR YLGFICILLI
     SYSMSISLIE GLWMSKVKQL YPDTKDFISY HGKVFFWTGV LTLVSAFLGS NLIRLCGWFW
     GAIITPIMMF GAGVMFFSFT VFENHLKNII DTLGYSSPLI VIVFIGGLWH VLSKSVKYSL
     FDATKEMVYI PLDSEMKTKG KAAVDVMGTK IGKSIGAIIQ FISFSIFPNA VHNDIAGLLM
     FSFIIVCLIW LYGVKVLAEY YNKLVKR