ID   TLCB_RICFE              Reviewed;         507 AA.
AC   Q4ULY0;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=ADP,ATP carrier protein 2;
DE   AltName: Full=ADP/ATP translocase 2;
GN   Name=tlcB; Synonyms=tlc2; OrderedLocusNames=RF_0592;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; CP000053; AAY61443.1; -; Genomic_DNA.
DR   RefSeq; WP_011270922.1; NC_007109.1.
DR   AlphaFoldDB; Q4ULY0; -.
DR   EnsemblBacteria; AAY61443; AAY61443; RF_0592.
DR   KEGG; rfe:RF_0592; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; HIVWPIR; -.
DR   OrthoDB; 427341at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..507
FT                   /note="ADP,ATP carrier protein 2"
FT                   /id="PRO_0000286469"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        333..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        451..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        474..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   507 AA;  58412 MW;  964C7A9E05E4182F CRC64;
     MDAVDSNFTI WNKARNSKFR HIVWPIRSYE LTKFIPMVLL MFFILLNQNL VRSIKDSFVV
     TLISSEVLSF IKLWGEMPMG ILFVILYSKL CNIMTTEQVF RIITGTFLFF FAIFGFILFP
     YREFFHPDPE LIKHYITVLP HLKWFLIIWG QWSLVLFYIM GELWPVIVFT LLYWQLANKI
     TKVEEAPRFY SFFTLFGQTN LLISGTVIIY FAKSEHFLLP LFSHLNDTNE ILLKSFITVI
     LISGLICLAL HKLIDKSVVE ADKNIKFKNQ RTDILKLSLV ESAKVILTSR YLGFICLLVM
     SYSMSISLIE GLWMSKVKQL YPATKDFISY HGEVFFWTGV LTLVSAFLGS SLIRICGWFW
     GAIITPIMMF GAGVMFFSFT VFENHLENIV NTLGYSLPLV VIVFIGGLWH VLSKSVKYSL
     FDATKEMVYI PLDSEMKTKG KAAVDVMGTK IGKSIGAIIQ FISFSIFPNA VHNDIAGLLM
     FSFVIVCLLW LYGVKVLSEQ YNKMIKR