ID   TLCC_RICCN              Reviewed;         501 AA.
AC   Q92HP9;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=ADP,ATP carrier protein 3;
DE   AltName: Full=ADP/ATP translocase 3;
GN   Name=tlcC; Synonyms=tlc3; OrderedLocusNames=RC0722;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; AE006914; AAL03260.1; -; Genomic_DNA.
DR   PIR; B97790; B97790.
DR   RefSeq; WP_010977341.1; NC_003103.1.
DR   AlphaFoldDB; Q92HP9; -.
DR   EnsemblBacteria; AAL03260; AAL03260; RC0722.
DR   KEGG; rco:RC0722; -.
DR   PATRIC; fig|272944.4.peg.822; -.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; HPNTIDY; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..501
FT                   /note="ADP,ATP carrier protein 3"
FT                   /id="PRO_0000286472"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        387..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        470..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   501 AA;  57105 MW;  2EC589FAD865EA3B CRC64;
     MLPPKIFFEK VKEIMWPIER KELKLFIPMA LMMLCILFNF GALRSIKDSL VVPSMGAEII
     SFLKLWLVLP SCVIFTVLYV KLSNNLNFEY IFYIIVGSFL LFFLLFAYII YPNQDIYHPN
     DEMINKLIAS YPNFKWFIKI GSQWSYALMY IFAELWSAVV INLMFWQFAN HIFDTSKAKR
     FYPVLGMVGN IGLIIAGSVL VFFSSGQDVI DSELLPDSFN SSAGNAIMLQ PIMSIIVTAG
     IIAMLLFRII NRFILTDSIN VLDAKKVTAK MKTKLSVIES IKLVIHSKYI GRIALLIICY
     GLLINIVEGP WKAKIKELHP NTIDYVNFMG RFNIWMGISC VTFMIIGSNI LRRLGWLISA
     LLTPIMLSIT GLMFFIFIIF IEEIGECFGD FNLLYAAIIV GAIQNILSKS SKYSLFDSTK
     EMAYIPLSLE LRTKGKAAVE VIGTKFGKSL GAFIQSLIFI IIPTATFDSI IIYLLITFIV
     MMSLWIWNVI KLNKEYVELC K