ID   TLCC_RICFE              Reviewed;         501 AA.
AC   Q4UL85;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=ADP,ATP carrier protein 3;
DE   AltName: Full=ADP/ATP translocase 3;
GN   Name=tlcC; Synonyms=tlc3; OrderedLocusNames=RF_0837;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; CP000053; AAY61688.1; -; Genomic_DNA.
DR   RefSeq; WP_011271165.1; NC_007109.1.
DR   AlphaFoldDB; Q4UL85; -.
DR   STRING; 315456.RF_0837; -.
DR   EnsemblBacteria; AAY61688; AAY61688; RF_0837.
DR   KEGG; rfe:RF_0837; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; HPNTIDY; -.
DR   OrthoDB; 427341at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..501
FT                   /note="ADP,ATP carrier protein 3"
FT                   /id="PRO_0000286473"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        470..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   501 AA;  57113 MW;  A924D9846A8062C4 CRC64;
     MLPPKIFFEK VKEIIWPIER KELKLFIPMA LMMLCILFNF GALRSIKDSL VVPSMGAEII
     SLFKLWLVLP SCVIFTVLYV KLSNKLNFEY IFYIIVGSFL LFFLLFAYII YPNQDIYHPN
     DEMINNLIAS YPNFKWFIKI GSKWSYALMY IFSELWSAVV INLMFWQFAN HIFDTSKAKR
     FYPVLGMVGN IGLIIAGSVL VFFSSGQEVI DSELLPDSFN SPAGNAIMLQ PIMSIIVAAG
     IIAMLLFRII NRFILTDSIN VLDTKKVTVK TKTKLSVIES IKLVIHSKYI GRIALLIICY
     GLLINIVEGP WKAKIKELHP NTIDYFNFMG RFNIWMGISC VTFMVIGSNI LRRLGWLISA
     LLTPIMLSIT GLMFFIFIIF IEEIGACFGD FNLLYAAIIV GAIQNILSKS SKYSLFDSTK
     EMAYIPLSLE LRTKGKAAVE VIGTKFGKSL GAFIQSLIFI IIPTATFDSI IIYLLVIFIV
     MMSLWIWNVI KLNKEYIELC K