ID   TLCC_RICPR              Reviewed;         501 AA.
AC   Q9ZD67;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=ADP,ATP carrier protein 3;
DE   AltName: Full=ADP/ATP translocase 3;
GN   Name=tlcC; Synonyms=tlc3; OrderedLocusNames=RP477;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; AJ235271; CAA14932.1; -; Genomic_DNA.
DR   PIR; B71707; B71707.
DR   RefSeq; NP_220856.1; NC_000963.1.
DR   RefSeq; WP_004599498.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZD67; -.
DR   STRING; 272947.RP477; -.
DR   EnsemblBacteria; CAA14932; CAA14932; CAA14932.
DR   KEGG; rpr:RP477; -.
DR   PATRIC; fig|272947.5.peg.489; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; HPNTIDY; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..501
FT                   /note="ADP,ATP carrier protein 3"
FT                   /id="PRO_0000102582"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        470..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   501 AA;  57182 MW;  D1EC540EE6D7E91F CRC64;
     MLPPKIFFEK VKEIIWPIER KELKLFIPMA LMMLCILFNF GALRSIKDSL VVPSMGAEII
     SFLKLWLVLP SCVIFTILYV KLSNKLNFEY IFYSIVGTFL LFFLLFAYII YPNQDIYHPN
     DAMINNLIAS YPNLKWFIKI GSKWSYALMY IFSELWSAVV INLMFWQFAN HIFDTAKAKR
     FYPVLGMVGN IGLIIAGSVL VFFSSGQYII DSELLTDSYN SSSNNSIMLQ PIISIIVTAG
     IIAMFLFRII NKFILTNSIN VLDVKKVAAK TKTKLALIES IKLIIHSKYI GRIALLIICY
     GLLINIVEGP WKAKIKELHP NTVDYVNFMG MFNIWMGISC VTFMIIGSNI LRRLGWLISA
     LLTPIMLSIT GFMFFIFIIF IEEIGTCFGD FNLLYVAIIV GAIQNILSKS SKYSLFDSTK
     EMAYIPLSLE LRTKGKAAVE VIGTKFGKSL GAFIQSLIFI IIPTATFDSI IIYLLVIFIV
     MMNLWIWNII KLNKEYIKLC Q