ID   TLCD_RICBR              Reviewed;         520 AA.
AC   Q1RIG3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=ADP,ATP carrier protein 4;
DE   AltName: Full=ADP/ATP translocase 4;
GN   Name=tlcD; Synonyms=tlc4; OrderedLocusNames=RBE_0770;
OS   Rickettsia bellii (strain RML369-C).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX   NCBI_TaxID=336407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RML369-C;
RX   PubMed=16703114; DOI=10.1371/journal.pgen.0020076;
RA   Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C.,
RA   Fournier P.-E., Claverie J.-M., Raoult D.;
RT   "Genome sequence of Rickettsia bellii illuminates the role of amoebae in
RT   gene exchanges between intracellular pathogens.";
RL   PLoS Genet. 2:733-744(2006).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; CP000087; ABE04851.1; -; Genomic_DNA.
DR   RefSeq; WP_011477438.1; NC_007940.1.
DR   AlphaFoldDB; Q1RIG3; -.
DR   STRING; 336407.RBE_0770; -.
DR   EnsemblBacteria; ABE04851; ABE04851; RBE_0770.
DR   KEGG; rbe:RBE_0770; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; FLMTAIY; -.
DR   OrthoDB; 427341at2; -.
DR   Proteomes; UP000001951; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..520
FT                   /note="ADP,ATP carrier protein 4"
FT                   /id="PRO_0000286484"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        399..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        462..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        485..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   520 AA;  58912 MW;  14FE3028AE0E71AB CRC64;
     MTINQNNSNH TFSSHNLDNS PHKINKLINK FSDYIWPIKR QELSKFLFIT LLMFCILFIQ
     NLIRALKDSI VTTMIGAETI SFLKFWGVMP CAFLMTAIYV KLVNRMKAEN IFYLIISIFL
     AFFALFAYVI FPNHEILHLS PTTAQNLIAS LPNLKWFILL LSKWSFSLFY IIAELWPNVA
     FALLFWQFVN NITTVEESKR FYPLFGLLSQ TGIYLAGQFL ENLSHINEYV VAKFSLQASF
     HTLSVQIILT IVLILGIVGI KTFWLLNHKV LDKEHMALLR FKAKKKTMTI AESFQMILSS
     RHIRLIATLL ICYGIAINLV EGPWKAAATK IYKTPTEYAA FIGNYLSYTG AFTILFVVLG
     SNIVRKLGWF TAAIITPIIV FTTGILFFAV NNFESSAGLI VASFILTDPA LIAITIGAIQ
     NVLSKSSKYT LFDSTKEMAY VPLDKEIKIK GKAAADVLGT KLGKSGSAFL QSLVFIILPS
     ASYQSISVCL MFIFIITCLI WFWAVKELNK EYKKSVKFSQ