ID   TLCD_RICCN              Reviewed;         511 AA.
AC   Q92HV4;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=ADP,ATP carrier protein 4;
DE   AltName: Full=ADP/ATP translocase 4;
GN   Name=tlcD; Synonyms=tlc4; OrderedLocusNames=RC0666;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; AE006914; AAL03204.1; -; Genomic_DNA.
DR   PIR; B97783; B97783.
DR   RefSeq; WP_010977290.1; NC_003103.1.
DR   AlphaFoldDB; Q92HV4; -.
DR   EnsemblBacteria; AAL03204; AAL03204; RC0666.
DR   KEGG; rco:RC0666; -.
DR   PATRIC; fig|272944.4.peg.759; -.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; FLMTAIY; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..511
FT                   /note="ADP,ATP carrier protein 4"
FT                   /id="PRO_0000286475"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        476..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   511 AA;  58036 MW;  E194D7E21591EE02 CRC64;
     MTINPSNVEN SSSKINSYFS KLTDYIWPIK RHEVSKFLFI TLLMFCILFI QNLIRALKDS
     IVTTMIGAEI ISFLKFWGVM PSAFLMTAIY VKLVNKMKAE NIFYLIISIF LTFFALFAYV
     IFPNHEMLHF SPVTVQNLMA SLPNLKWFIW LLSKWSFSLF YIIAELWPNV VFALLFWQFV
     NNITTVEESK RFYPLFGLLS QTGIYLAGQF LENLSNINDY VTNKFALQSS FHTLSIQIIL
     TIVLILGIIA IKTFWLLNHK VLDKEHMALL RFKAKKKSMT IAESFQMLLS SRHIRLIATL
     LICYGIAINL VEGPWKAAAT KIYKTPTEYA AFIGSYLSYT GVFTILFVVL GSNIVRRLGW
     FTAAVITPLI VFITGILFFA VNNFERFAGL IIANFILTDP ALIAITIGAI QNVLSKSSKY
     TLFDSTKEMA YVPLDPEIKI KGKAAADVIG TKLGKSGSAF LQSLVFIILP SASYQSISTC
     LMIIFIITCL TWLWATKALN KEYKNSIKFS Q