ID   TLCD_RICFE              Reviewed;         511 AA.
AC   Q4ULJ8;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=ADP,ATP carrier protein 4;
DE   AltName: Full=ADP/ATP translocase 4;
GN   Name=tlcD; Synonyms=tlc4; OrderedLocusNames=RF_0724;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; CP000053; AAY61575.1; -; Genomic_DNA.
DR   RefSeq; WP_011271054.1; NC_007109.1.
DR   AlphaFoldDB; Q4ULJ8; -.
DR   STRING; 315456.RF_0724; -.
DR   EnsemblBacteria; AAY61575; AAY61575; RF_0724.
DR   KEGG; rfe:RF_0724; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; FLMTAIY; -.
DR   OrthoDB; 427341at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..511
FT                   /note="ADP,ATP carrier protein 4"
FT                   /id="PRO_0000286476"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        476..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   511 AA;  57870 MW;  B64A98B2F1F04533 CRC64;
     MTINSSNIEN PPSKINSRFS KLTDYIWPIK RHEVSKFLFI TLLMFCILFI QNLIRALKDS
     IVTTMIGAET ISFLKFWGVM PSAFLMTAIY VKLVNRMKAE NIFYLIISIF LAFFALFAYV
     IFPNHEILHL SPVTVQNLTA NLLNLKWFIL LLSKWSFSLF YIIAELWPNV VFALLFWQFV
     NNITTVEESK RFYPLFGLLS QTGIYLAGQF LENLSNINDY VTNKFALQSS FHTLSIQIIL
     TIVLILGIIA IKTFWLLNHK VLDKEHMALL KFKAKKKSMT IAESFQMILS SRHIRLIATL
     LICYGIAINL VEGPWKAAAT KIYKTPTEYA AFIGSYLSYT GVFTILFVVL GSNIVRRLGW
     FTAAVITPLI VFITGILFFA VNNFEGFAGL IIANFILTDP ALIAITIGAI QNVLSKSSKY
     TLFDSTKEMA YVPLDPEIKI KGKAAADVIG TKLGKSGSAF LQSLVFIILP SASYQSISIC
     LMIIFIITCL TWLWATKELN KEYKNSIKFS Q