ID   TLCE_RICCN              Reviewed;         499 AA.
AC   Q92GI5;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=ADP,ATP carrier protein 5;
DE   AltName: Full=ADP/ATP translocase 5;
GN   Name=tlcE; Synonyms=tlc5; OrderedLocusNames=RC1138;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006914; AAL03676.1; -; Genomic_DNA.
DR   PIR; B97842; B97842.
DR   RefSeq; WP_010977709.1; NC_003103.1.
DR   AlphaFoldDB; Q92GI5; -.
DR   EnsemblBacteria; AAL03676; AAL03676; RC1138.
DR   KEGG; rco:RC1138; -.
DR   PATRIC; fig|272944.4.peg.1310; -.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; TSKEMLY; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..499
FT                   /note="ADP,ATP carrier protein 5"
FT                   /id="PRO_0000286478"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        327..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        468..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   499 AA;  56919 MW;  CDB73E469763E2AF CRC64;
     MLSTSSRSFK NKFRAAFWPV HNYELGKFIP MSTLMFCILF NQNVLRILKD SILISEISAE
     IAGFAKVYCV TPAAALFVII YAKMINYLTF EKIFYYLSAF FISFFVLFTF VIYPNIHIFH
     VHPNNLADWM ERYPHFKWYI SLVGNWGYIV YYSLAELWPN IFYVLLFWQF ANELTTTEEA
     KRFYTLFSLF GNSSLILVGF LMMNLSSEDT IIKKFMSISD SKITLVQVST TIVAIVAIIC
     CLLVRFISKN VFTNPLFYAK AKSGRSTSER MGLIKSFKYI AKSKYLWLLL ICSAAFGFAI
     NLVEAVWKAK IKELYPTVNT YAEFNSLYIL WTGVAIMVMT IIGNNIMRMH NWFVAAVISP
     VIIMVTGILF FVLIVFDQQI LSLFDGAILM SPLALAVSIG GIQNILAKGT KYSIWDTSRE
     MLYIPLDEEL KTKGKAAVDV ISAKVGKSSS GLVQSIIFTL VPTATFTLIS PILMVVFTFV
     CLAWIYAVRK IYCEYQKIA