ID   TLCE_RICFE              Reviewed;         499 AA.
AC   Q4UN46;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=ADP,ATP carrier protein 5;
DE   AltName: Full=ADP/ATP translocase 5;
GN   Name=tlcE; Synonyms=tlc5; OrderedLocusNames=RF_0161;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; CP000053; AAY61012.1; -; Genomic_DNA.
DR   RefSeq; WP_011270513.1; NC_007109.1.
DR   AlphaFoldDB; Q4UN46; -.
DR   STRING; 315456.RF_0161; -.
DR   EnsemblBacteria; AAY61012; AAY61012; RF_0161.
DR   KEGG; rfe:RF_0161; -.
DR   eggNOG; COG3202; Bacteria.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   OMA; TSKEMLY; -.
DR   OrthoDB; 427341at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   PANTHER; PTHR31187; PTHR31187; 1.
DR   Pfam; PF03219; TLC; 1.
DR   TIGRFAMs; TIGR00769; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..499
FT                   /note="ADP,ATP carrier protein 5"
FT                   /id="PRO_0000286479"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        327..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        468..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   499 AA;  56856 MW;  07701BA22105E10F CRC64;
     MLSTSSRSFK SKFRAAFWPV HNYELGKFIP MSALMFCILF NQNILRILKD SILISEISAE
     IAGFAKVYCV TPAAALFVII YAKMINRFTF EKIFYYLSAF FISFFVLFAF VIYPNIHVFH
     VHPDNLADWM ERYPHFKWYI SLVGNWGYIV YYSLAELWPN IFYVLLFWQF ANELTTTEEA
     KRFYTFFSLF GNSSLILVGF LMMNLSSEDT IIKKFMSISD SKITLVQVST TIVAIVAIVC
     CVLVRFISKN VFTNPLFYAK AKSGRSTSER MGLIKSFKYI AKSKYLWLLL ICSAAFGFAI
     NLVEAVWKAK IKELYPTVNT YAEFNSLYIL WTGVAIMVMT IIGNNVMRMH NWFVAAVISP
     VIIMVTGILF FVLIVFDQQI LSLFDGAILM SPLALAVSIG GIQNILAKGT KYSIWDTSRE
     MLYIPLDDEL KTKGKAAVDV ISAKVGKSSS GLVQSIIFTL VPTATFTSIS PILMVVFTFV
     CLAWIYAVRK IYFEYQKIA