ID   TLDD_BUCAP              Reviewed;         483 AA.
AC   Q8K9F2;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Metalloprotease TldD homolog;
DE            EC=3.4.-.-;
GN   Name=tldD; OrderedLocusNames=BUsg_385;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- FUNCTION: Probable metalloprotease. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE013218; AAM67937.1; -; Genomic_DNA.
DR   RefSeq; WP_011053904.1; NC_004061.1.
DR   AlphaFoldDB; Q8K9F2; -.
DR   SMR; Q8K9F2; -.
DR   STRING; 198804.BUsg_385; -.
DR   EnsemblBacteria; AAM67937; AAM67937; BUsg_385.
DR   KEGG; bas:BUsg_385; -.
DR   eggNOG; COG0312; Bacteria.
DR   HOGENOM; CLU_026425_1_0_6; -.
DR   OMA; TDFWGSM; -.
DR   OrthoDB; 806701at2; -.
DR   Proteomes; UP000000416; Chromosome.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; -; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR025502; TldD.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   Pfam; PF01523; PmbA_TldD; 1.
DR   Pfam; PF19289; PmbA_TldD_C; 1.
DR   Pfam; PF19290; PmbA_TldD_M; 1.
DR   PIRSF; PIRSF004919; TldD; 1.
DR   SUPFAM; SSF111283; SSF111283; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Metalloprotease; Protease.
FT   CHAIN           1..483
FT                   /note="Metalloprotease TldD homolog"
FT                   /id="PRO_0000142355"
SQ   SEQUENCE   483 AA;  53564 MW;  E7C387C8B8A25D0F CRC64;
     MTLELVTESL LTKNQINHQD VFSCLEDFCT HNIDYGDFYF QSRICESWSL ENGIIKEGDY
     HLDQGVGVRA VSGETTGFSY ADQISIDAVR KSAHMAKSIF DKKEKIKIKP LLNQEKKFFY
     DPINPLKTFT SSEKTNLLYK VDHIARKTDN RVVQVNANLS GSYEEILVVS TEGNLATDIR
     PLVEFSVSVL VEERGRREKG RSGGGSRTNY SFFITQDDCF GENRIDYWTK EAVRIALLNL
     SSHEAPSGTF PVVLGSGWPG VLLHEAVGHG LEGDFNRRGT SIFTNMIEKK VASELCTIID
     DGTMKNQRGS LNIDDEGVPG QCNVLIENGI LKKYMQDKLN ARLMNTKSTG NGRRESYSHL
     PMPRMTNTYM IPGKSKLEDI INSVDYGIYA INFSGGQVDI TSGQFVFSTS EAYLVKKGKI
     FSPIRNTTLI GSGLEVMQQI SMVGNDLKMD QGMGMCGKDG QNIPVGIGQP SIKLEKLTVG
     GTV