TLG1_SCHPO
ID TLG1_SCHPO Reviewed; 225 AA.
AC Q9HGN3;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=t-SNARE affecting a late Golgi compartment protein 1;
DE AltName: Full=Syntaxin tlg1;
GN Name=tlg1; ORFNames=SPBC36B7.07;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane
CC {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
CC Endosome membrane {ECO:0000250}; Single-pass type IV membrane protein
CC {ECO:0000250}. Note=Probably shuttling between TGN and early/late
CC endosome. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the syntaxin family. {ECO:0000305}.
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DR EMBL; CU329671; CAC05728.1; -; Genomic_DNA.
DR RefSeq; NP_595989.1; NM_001021896.2.
DR AlphaFoldDB; Q9HGN3; -.
DR SMR; Q9HGN3; -.
DR BioGRID; 277489; 2.
DR STRING; 4896.SPBC36B7.07.1; -.
DR iPTMnet; Q9HGN3; -.
DR MaxQB; Q9HGN3; -.
DR PaxDb; Q9HGN3; -.
DR PRIDE; Q9HGN3; -.
DR EnsemblFungi; SPBC36B7.07.1; SPBC36B7.07.1:pep; SPBC36B7.07.
DR GeneID; 2540973; -.
DR KEGG; spo:SPBC36B7.07; -.
DR PomBase; SPBC36B7.07; tlg1.
DR VEuPathDB; FungiDB:SPBC36B7.07; -.
DR eggNOG; KOG3202; Eukaryota.
DR HOGENOM; CLU_061883_0_2_1; -.
DR InParanoid; Q9HGN3; -.
DR OMA; EHDPYRF; -.
DR PhylomeDB; Q9HGN3; -.
DR Reactome; R-SPO-6811440; Retrograde transport at the Trans-Golgi-Network.
DR PRO; PR:Q9HGN3; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; ISS:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; ISS:PomBase.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0006896; P:Golgi to vacuole transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0048278; P:vesicle docking; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR015260; Syntaxin-6_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; PTHR19957; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF09177; Syntaxin-6_N; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; SSF47661; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil; Endosome; Golgi apparatus; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..225
FT /note="t-SNARE affecting a late Golgi compartment protein
FT 1"
FT /id="PRO_0000210276"
FT TOPO_DOM 1..204
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT DOMAIN 133..195
FT /note="t-SNARE coiled-coil homology"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT COILED 38..68
FT /evidence="ECO:0000255"
SQ SEQUENCE 225 AA; 24970 MW; 0A39E08DA6CEAD08 CRC64;
MEDPFYEVKA DASNQMEQVR KLYNSFMAAR NSGVLSPNTE LTYAIDELSE TLKDLKAAVE
IAMKNSEHFG LDEEELKSRR RFVSELDIEL NNIQLKMGAA PSTPVSTEPY TVDNGASAGL
SEEDHAVNRQ YQEQLYQQQD VMLDGVYDTI GNIRGQAALM GEELGQQADL LDTLDNSIET
TNSKLRRGMK RLKDFTIASA DSKSGCCITV LIIILIALLV LVIVL
