TLP1A_MANZA
ID TLP1A_MANZA Reviewed; 12 AA.
AC B3EWS0;
DT 09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2013, sequence version 1.
DT 11-DEC-2019, entry version 11.
DE RecName: Full=Thaumatin-like protein 1a;
DE EC=3.2.1.-;
DE AltName: Full=Acidic thaumatin-like protein;
DE AltName: Full=Beta-1,3-glucanase;
DE Flags: Fragment;
OS Manilkara zapota (Sapodilla plum) (Achras zapota).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Sapotaceae; Sapotoideae; Manilkara.
OX NCBI_TaxID=3741;
RN [1]
RP PROTEIN SEQUENCE, FUNCTION, SUBUNIT, LACK OF GLYCOSYLATION, AND
RP ALLERGENICITY.
RC STRAIN=cv. Cricket Ball; TISSUE=Fruit;
RX PubMed=24060761; DOI=10.2332/allergolint.12-oa-0522;
RA Ashok Kumar H.G., Hegde V.L., Shetty S.M., Venkatesh Y.P.;
RT "Characterization and gene cloning of an acidic thaumatin-like protein (TLP
RT 1), an allergen from sapodilla fruit (Manilkara zapota).";
RL Allergol. Int. 62:447-462(2013).
CC -!- FUNCTION: Has weak beta-1,3-glucanase activity with laminarin as
CC substrate. {ECO:0000269|PubMed:24060761}.
CC -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:24060761}.
CC -!- PTM: Not glycosylated.
CC -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC {ECO:0000269|PubMed:24060761}.
CC -!- MISCELLANEOUS: On the 2D-gel the determined pI of this protein is: 4.4.
CC -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00699}.
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DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Allergen; Direct protein sequencing; Disulfide bond; Glycosidase;
KW Hydrolase.
FT CHAIN 1..>12
FT /note="Thaumatin-like protein 1a"
FT /id="PRO_0000420801"
FT DISULFID 9..?
FT /evidence="ECO:0000250|UniProtKB:G5DC91,
FT ECO:0000255|PROSITE-ProRule:PRU00699"
FT NON_TER 12
SQ SEQUENCE 12 AA; 1360 MW; 08AB4FFAA3D452C0 CRC64;
ATFDIVNQCT FT