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TLP1A_MANZA
ID   TLP1A_MANZA             Reviewed;          12 AA.
AC   B3EWS0;
DT   09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 1.
DT   11-DEC-2019, entry version 11.
DE   RecName: Full=Thaumatin-like protein 1a;
DE            EC=3.2.1.-;
DE   AltName: Full=Acidic thaumatin-like protein;
DE   AltName: Full=Beta-1,3-glucanase;
DE   Flags: Fragment;
OS   Manilkara zapota (Sapodilla plum) (Achras zapota).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; Ericales; Sapotaceae; Sapotoideae; Manilkara.
OX   NCBI_TaxID=3741;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, LACK OF GLYCOSYLATION, AND
RP   ALLERGENICITY.
RC   STRAIN=cv. Cricket Ball; TISSUE=Fruit;
RX   PubMed=24060761; DOI=10.2332/allergolint.12-oa-0522;
RA   Ashok Kumar H.G., Hegde V.L., Shetty S.M., Venkatesh Y.P.;
RT   "Characterization and gene cloning of an acidic thaumatin-like protein (TLP
RT   1), an allergen from sapodilla fruit (Manilkara zapota).";
RL   Allergol. Int. 62:447-462(2013).
CC   -!- FUNCTION: Has weak beta-1,3-glucanase activity with laminarin as
CC       substrate. {ECO:0000269|PubMed:24060761}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:24060761}.
CC   -!- PTM: Not glycosylated.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC       {ECO:0000269|PubMed:24060761}.
CC   -!- MISCELLANEOUS: On the 2D-gel the determined pI of this protein is: 4.4.
CC   -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00699}.
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DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond; Glycosidase;
KW   Hydrolase.
FT   CHAIN           1..>12
FT                   /note="Thaumatin-like protein 1a"
FT                   /id="PRO_0000420801"
FT   DISULFID        9..?
FT                   /evidence="ECO:0000250|UniProtKB:G5DC91,
FT                   ECO:0000255|PROSITE-ProRule:PRU00699"
FT   NON_TER         12
SQ   SEQUENCE   12 AA;  1360 MW;  08AB4FFAA3D452C0 CRC64;
     ATFDIVNQCT FT
 
 
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