TLP1_ARATH
ID TLP1_ARATH Reviewed; 455 AA.
AC Q9ZP59;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Tubby-like F-box protein 1;
DE Short=AtTLP1;
GN Name=TULP1; OrderedLocusNames=At1g76900; ORFNames=F22K20.1, F7O12.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=15064372; DOI=10.1104/pp.103.037820;
RA Lai C.-P., Lee C.-L., Chen P.-H., Wu S.-H., Yang C.-C., Shaw J.-F.;
RT "Molecular analyses of the Arabidopsis TUBBY-like protein gene family.";
RL Plant Physiol. 134:1586-1597(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- INTERACTION:
CC Q9ZP59; Q9C8Y3: RGL1; NbExp=3; IntAct=EBI-4476686, EBI-963647;
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:15064372}.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000305}.
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DR EMBL; AF487267; AAQ06240.1; -; mRNA.
DR EMBL; AC002291; AAC00626.1; -; Genomic_DNA.
DR EMBL; AC079283; AAG51146.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35900.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35901.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61194.1; -; Genomic_DNA.
DR EMBL; AY139758; AAM98079.1; -; mRNA.
DR EMBL; BT003039; AAO23604.1; -; mRNA.
DR PIR; H96797; H96797.
DR RefSeq; NP_001319391.1; NM_001334747.1.
DR RefSeq; NP_177816.1; NM_106341.2.
DR RefSeq; NP_849894.1; NM_179563.3.
DR AlphaFoldDB; Q9ZP59; -.
DR SMR; Q9ZP59; -.
DR BioGRID; 29244; 5.
DR IntAct; Q9ZP59; 3.
DR STRING; 3702.AT1G76900.2; -.
DR iPTMnet; Q9ZP59; -.
DR PaxDb; Q9ZP59; -.
DR PRIDE; Q9ZP59; -.
DR ProteomicsDB; 234618; -.
DR EnsemblPlants; AT1G76900.1; AT1G76900.1; AT1G76900.
DR EnsemblPlants; AT1G76900.2; AT1G76900.2; AT1G76900.
DR EnsemblPlants; AT1G76900.3; AT1G76900.3; AT1G76900.
DR GeneID; 844025; -.
DR Gramene; AT1G76900.1; AT1G76900.1; AT1G76900.
DR Gramene; AT1G76900.2; AT1G76900.2; AT1G76900.
DR Gramene; AT1G76900.3; AT1G76900.3; AT1G76900.
DR KEGG; ath:AT1G76900; -.
DR Araport; AT1G76900; -.
DR TAIR; locus:2025327; AT1G76900.
DR eggNOG; KOG2502; Eukaryota.
DR HOGENOM; CLU_028236_3_0_1; -.
DR InParanoid; Q9ZP59; -.
DR OMA; HCAMNSI; -.
DR OrthoDB; 1445357at2759; -.
DR PhylomeDB; Q9ZP59; -.
DR PRO; PR:Q9ZP59; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZP59; baseline and differential.
DR Genevisible; Q9ZP59; AT.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 3.20.90.10; -; 2.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01167; Tub; 1.
DR PRINTS; PR01573; SUPERTUBBY.
DR SUPFAM; SSF54518; SSF54518; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS01200; TUB_1; 1.
DR PROSITE; PS01201; TUB_2; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..455
FT /note="Tubby-like F-box protein 1"
FT /id="PRO_0000272229"
FT DOMAIN 54..112
FT /note="F-box"
FT REGION 386..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..402
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 51195 MW; 53072DE655960C3E CRC64;
MSFRSIVRDV RDSIGSLSRR SFDFKLSSLN KEGGKSRGSV QDSHEEQLVV TIQETPWANL
PPELLRDVIK RLEESESVWP ARRHVVACAS VCRSWRDMCK EIVQSPELSG KITFPVSLKQ
PGPRDATMQC FIKRDKSNLT YHLYLCLSPA LLVENGKFLL SAKRIRRTTY TEYVISMHAD
TISRSSNTYI GKIRSNFLGT KFIIYDTQPA YNSNIARAVQ PVGLSRRFYS KRVSPKVPSG
SYKIAQVSYE LNVLGTRGPR RMHCAMNSIP ASSLAEGGTV PGQPDIIVPR SILDESFRSI
TSSSSRKITY DYSNDFSSAR FSDILGPLSE DQEVVLEEGK ERNSPPLVLK NKPPRWHEQL
QCWCLNFRGR VTVASVKNFQ LIAANQPQPQ PQPQPQPQPL TQPQPSGQTD GPDKIILQFG
KVGKDMFTMD FRYPLSAFQA FAICLSSFDT KLACE