ID   TLP1_CASSA              Reviewed;         243 AA.
AC   Q9SMH2;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Thaumatin-like protein 1;
DE   Flags: Precursor;
GN   Name=TL1;
OS   Castanea sativa (Sweet chestnut).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fagales; Fagaceae; Castanea.
OX   NCBI_TaxID=21020 {ECO:0000312|EMBL:CAB62167.1};
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Cotyledon;
RA   Garcia-Casado G., Gomez L., Aragoncillo C.;
RT   "An apoplastic basic thaumatin-like protein from recalcitrant chestnut
RT   seeds with antifungal properties.";
RL   Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possesses antifungal activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00699}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ242828; CAB62167.1; -; mRNA.
DR   AlphaFoldDB; Q9SMH2; -.
DR   SMR; Q9SMH2; -.
DR   Allergome; 10208; Cas s TLP.
DR   PRIDE; Q9SMH2; -.
DR   GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.110.10; -; 1.
DR   InterPro; IPR037176; Osmotin/thaumatin-like_sf.
DR   InterPro; IPR001938; Thaumatin.
DR   InterPro; IPR017949; Thaumatin_CS.
DR   PANTHER; PTHR31048; PTHR31048; 1.
DR   Pfam; PF00314; Thaumatin; 1.
DR   PIRSF; PIRSF002703; Thaumatin; 1.
DR   PRINTS; PR00347; THAUMATIN.
DR   SMART; SM00205; THN; 1.
DR   SUPFAM; SSF49870; SSF49870; 1.
DR   PROSITE; PS00316; THAUMATIN_1; 1.
DR   PROSITE; PS51367; THAUMATIN_2; 1.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Apoplast; Disulfide bond; Fungicide; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..243
FT                   /note="Thaumatin-like protein 1"
FT                   /id="PRO_0000034019"
FT   DISULFID        31..242
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        79..88
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        93..100
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        148..231
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        153..214
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        161..177
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        181..190
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   DISULFID        191..201
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
SQ   SEQUENCE   243 AA;  25835 MW;  E3FF0B3634DD5E1A CRC64;
     MMKTLALYGL TLALFFLSGA HSAKITFTNN CPRTIWPGTL TSDQKPQLPN TGFVLASKAS
     LTLGVQAPWK GRFWARTRCT TNSGKFTCET ADCSTGQVAC NGNGAIPPAS LVEINIAANR
     GMDFYDVSLV DGYNLPVSVA TRGGTGDCKA TSCRANVNAV CPAELQVKGS DASVLACKSA
     CTAFNQPQYC CTGAFDTART CPATKYSRIF KQQCPQAYSY AYDDSTSTFT CSGAPDYVIT
     FCP