TLP20_NPVAC
ID TLP20_NPVAC Reviewed; 180 AA.
AC Q06691; Q64806;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-1998, sequence version 2.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Telokin-like protein 20;
GN Name=TLP20;
OS Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=46015;
OH NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6;
RX PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT virus.";
RL Virology 202:586-605(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=E2;
RX PubMed=8126447; DOI=10.1099/0022-1317-75-3-487;
RA Kool M., Broer R., Zuidema D., Goldbach R.W., Vlak J.M.;
RT "Nucleotide sequence and genetic organization of a 7.3 kb region (map unit
RT 47 to 52.5) of Autographa californica nuclear polyhedrosis virus fragment
RT EcoRI-C.";
RL J. Gen. Virol. 75:487-494(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=7517434; DOI=10.1099/0022-1317-75-7-1807;
RA Raynes D.A., Hartshorne D.J., Guerriero V.;
RT "Sequence and expression of a baculovirus protein with antigenic similarity
RT to telokin.";
RL J. Gen. Virol. 75:1807-1809(1994).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 7-108.
RX PubMed=15299576; DOI=10.1107/s0907444996008128;
RA Holden H.M., Wesenberg G., Raynes D.A., Hartshorne D.J., Guerriero V. Jr.,
RA Rayment I.;
RT "Molecular structure of a proteolytic fragment of TLP20.";
RL Acta Crystallogr. D 52:1153-1160(1996).
CC -!- MISCELLANEOUS: Shares some antigenic similarities to the smooth muscle
CC protein telokin, but is not similar at the sequence level.
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DR EMBL; L22858; AAA66712.1; -; Genomic_DNA.
DR EMBL; X71415; CAA50545.1; -; Genomic_DNA.
DR EMBL; U06931; AAA20084.1; -; mRNA.
DR PIR; C72860; C72860.
DR PIR; S36698; S36698.
DR RefSeq; NP_054112.1; NC_001623.1.
DR PDB; 1TUL; X-ray; 2.20 A; A=1-108.
DR PDBsum; 1TUL; -.
DR SMR; Q06691; -.
DR PRIDE; Q06691; -.
DR GeneID; 1403915; -.
DR KEGG; vg:1403915; -.
DR EvolutionaryTrace; Q06691; -.
DR Proteomes; UP000008292; Genome.
DR CDD; cd00235; TLP-20; 1.
DR Gene3D; 2.70.40.20; -; 1.
DR InterPro; IPR009092; Telokin-like_Tlp20_baculovir.
DR InterPro; IPR036731; Tlp20_sf.
DR Pfam; PF06088; TLP-20; 1.
DR SUPFAM; SSF51289; SSF51289; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..180
FT /note="Telokin-like protein 20"
FT /id="PRO_0000132851"
FT REGION 112..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 39..41
FT /note="GVG -> ALA (in Ref. 2; CAA50545)"
FT /evidence="ECO:0000305"
FT CONFLICT 130
FT /note="E -> A (in Ref. 1; AAA66712)"
FT /evidence="ECO:0000305"
FT STRAND 11..17
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 24..29
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 33..35
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 41..47
FT /evidence="ECO:0007829|PDB:1TUL"
FT HELIX 51..57
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 59..74
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 84..91
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 93..95
FT /evidence="ECO:0007829|PDB:1TUL"
FT STRAND 100..107
FT /evidence="ECO:0007829|PDB:1TUL"
SQ SEQUENCE 180 AA; 19810 MW; E9728661756D9D86 CRC64;
MASMSNITPD IIVNAQINSE DENVLDFIIE DEYYLKKRGV GAHIIKVASS PQLRLLYKNA
YSTVSCGNYG VLCNLVQNGE YDLNAIMFNC AEIKLNKGQM LFQTKIWRSD NSKTDAAVHT
SSPKRTVETE NDDDGEAASA AAIDEQEGNA DVVGLDFEEN IDDGDAPTPK KQKLDNAKQD
