TLP5_ARATH
ID TLP5_ARATH Reviewed; 429 AA.
AC Q944S3; Q9XIF9;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Tubby-like F-box protein 5;
DE Short=AtTLP5;
GN Name=TULP5; OrderedLocusNames=At1g43640; ORFNames=T10P12.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=15064372; DOI=10.1104/pp.103.037820;
RA Lai C.-P., Lee C.-L., Chen P.-H., Wu S.-H., Yang C.-C., Shaw J.-F.;
RT "Molecular analyses of the Arabidopsis TUBBY-like protein gene family.";
RL Plant Physiol. 134:1586-1597(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- TISSUE SPECIFICITY: Mostly expressed in roots, flowers and siliques.
CC {ECO:0000269|PubMed:15064372}.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD39275.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY046921; AAL03977.1; -; mRNA.
DR EMBL; AC007203; AAD39275.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31979.1; -; Genomic_DNA.
DR EMBL; AF424565; AAL11559.1; -; mRNA.
DR EMBL; AY072154; AAL59976.1; -; mRNA.
DR EMBL; AY122972; AAM67505.1; -; mRNA.
DR PIR; F96499; F96499.
DR RefSeq; NP_564485.1; NM_103489.3.
DR AlphaFoldDB; Q944S3; -.
DR SMR; Q944S3; -.
DR BioGRID; 26173; 1.
DR STRING; 3702.AT1G43640.1; -.
DR PaxDb; Q944S3; -.
DR PRIDE; Q944S3; -.
DR ProteomicsDB; 234333; -.
DR EnsemblPlants; AT1G43640.1; AT1G43640.1; AT1G43640.
DR GeneID; 840948; -.
DR Gramene; AT1G43640.1; AT1G43640.1; AT1G43640.
DR KEGG; ath:AT1G43640; -.
DR Araport; AT1G43640; -.
DR TAIR; locus:2194686; AT1G43640.
DR eggNOG; KOG2502; Eukaryota.
DR HOGENOM; CLU_028236_3_0_1; -.
DR InParanoid; Q944S3; -.
DR OrthoDB; 1445357at2759; -.
DR PhylomeDB; Q944S3; -.
DR PRO; PR:Q944S3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q944S3; baseline and differential.
DR Genevisible; Q944S3; AT.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0009620; P:response to fungus; IMP:TAIR.
DR Gene3D; 3.20.90.10; -; 1.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01167; Tub; 1.
DR PRINTS; PR01573; SUPERTUBBY.
DR SUPFAM; SSF54518; SSF54518; 1.
DR PROSITE; PS01200; TUB_1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..429
FT /note="Tubby-like F-box protein 5"
FT /id="PRO_0000272233"
FT DOMAIN 53..108
FT /note="F-box"
FT REGION 360..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 47845 MW; DC1E315A4C202556 CRC64;
MSFLSIVRDV RDTVGSFSRR SFDVRVSNGT THQRSKSHGV EAHIEDLIVI KNTRWANLPA
ALLRDVMKKL DESESTWPAR KQVVACAGVC KTWRLMCKDI VKSPEFSGKL TFPVSLKQPG
PRDGIIQCYI KRDKSNMTYH LYLSLSPAIL VESGKFLLSA KRSRRATYTE YVISMDADNI
SRSSSTYIGK LKSNFLGTKF IVYDTAPAYN SSQILSPPNR SRSFNSKKVS PKVPSGSYNI
AQVTYELNLL GTRGPRRMNC IMHSIPSLAL EPGGTVPSQP EFLQRSLDES FRSIGSSKIV
NHSGDFTRPK EEEGKVRPLV LKTKPPRWLQ PLRCWCLNFK GRVTVASVKN FQLMSAATVQ
PGSGSDGGAL ATRPSLSPQQ PEQSNHDKII LHFGKVGKDM FTMDYRYPLS AFQAFAISLS
TFDTKLACE