TLP6_ARATH
ID TLP6_ARATH Reviewed; 413 AA.
AC Q0WPY0; Q9C6B4;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Tubby-like F-box protein 6;
DE Short=AtTLP6;
GN Name=TULP6; OrderedLocusNames=At1g47270; ORFNames=F8G22.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 26-413, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=15064372; DOI=10.1104/pp.103.037820;
RA Lai C.-P., Lee C.-L., Chen P.-H., Wu S.-H., Yang C.-C., Shaw J.-F.;
RT "Molecular analyses of the Arabidopsis TUBBY-like protein gene family.";
RL Plant Physiol. 134:1586-1597(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q0WPY0-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Ubiquitous, with higher levels in flowers.
CC {ECO:0000269|PubMed:15064372}.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG52638.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC079677; AAG52638.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE32146.1; -; Genomic_DNA.
DR EMBL; AK228930; BAF00819.1; -; mRNA.
DR EMBL; AF487268; AAQ06241.1; -; mRNA.
DR PIR; E96513; E96513.
DR RefSeq; NP_001322089.1; NM_001333268.1.
DR RefSeq; NP_175160.2; NM_103621.2. [Q0WPY0-1]
DR AlphaFoldDB; Q0WPY0; -.
DR SMR; Q0WPY0; -.
DR BioGRID; 26355; 5.
DR STRING; 3702.AT1G47270.1; -.
DR PaxDb; Q0WPY0; -.
DR PRIDE; Q0WPY0; -.
DR EnsemblPlants; AT1G47270.1; AT1G47270.1; AT1G47270. [Q0WPY0-1]
DR GeneID; 841130; -.
DR Gramene; AT1G47270.1; AT1G47270.1; AT1G47270. [Q0WPY0-1]
DR KEGG; ath:AT1G47270; -.
DR Araport; AT1G47270; -.
DR TAIR; locus:2036730; AT1G47270.
DR eggNOG; KOG2502; Eukaryota.
DR InParanoid; Q0WPY0; -.
DR OrthoDB; 1445357at2759; -.
DR PhylomeDB; Q0WPY0; -.
DR PRO; PR:Q0WPY0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q0WPY0; baseline and differential.
DR Genevisible; Q0WPY0; AT.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009555; P:pollen development; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 3.20.90.10; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01167; Tub; 1.
DR PRINTS; PR01573; SUPERTUBBY.
DR SUPFAM; SSF54518; SSF54518; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS01200; TUB_1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..413
FT /note="Tubby-like F-box protein 6"
FT /id="PRO_0000272234"
FT DOMAIN 67..122
FT /note="F-box"
SQ SEQUENCE 413 AA; 46065 MW; 56DC573373C1F11A CRC64;
MDLSLLLPKR SWEISGGADK ISRVAMSLKN IVKNKYKAIG RRGRSHIAPE GSSVSSSLST
NEGLNQSIWV DLPPELLLDI IQRIESEQSL WPGRRDVVAC ASVCKSWREM TKEVVKVPEL
SGLITFPISL RQPGPRDAPI QCFIKRERAT GIYRLYLGLS PALSGDKSKL LLSAKRVRRA
TGAEFVVSLS GNDFSRSSSN YIGKLRSNFL GTKFTVYENQ PPPFNRKLPP SMQVSPWVSS
SSSSYNIASI LYELNVLRTR GPRRMQCIMH SIPISAIQEG GKIQSPTEFT NQGKKKKKPL
MDFCSGNLGG ESVIKEPLIL KNKSPRWHEQ LQCWCLNFKG RVTVASVKNF QLVAAAAEAG
KNMNIPEEEQ DRVILQFGKI GKDIFTMDYR YPISAFQAFA ICLSSFDTKP VCE