ID   TLP6_ORYSJ              Reviewed;         403 AA.
AC   Q10LG8; Q0DRV7; Q10LG7;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Tubby-like F-box protein 6;
DE            Short=OsTLP6;
DE   AltName: Full=Tubby-like F-box protein 14;
DE            Short=OsTLP14;
GN   Name=TULP6; Synonyms=TULP14;
GN   OrderedLocusNames=Os03g0351400, LOC_Os03g22800; ORFNames=OsJ_010398;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18070109; DOI=10.1111/j.1742-4658.2007.06186.x;
RA   Liu Q.;
RT   "Identification of rice TUBBY-like genes and their evolution.";
RL   FEBS J. 275:163-171(2008).
RN   [8]
RP   TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18620041; DOI=10.1016/j.ygeno.2008.06.001;
RA   Yang Z., Zhou Y., Wang X., Gu S., Yu J., Liang G., Yan C., Xu C.;
RT   "Genomewide comparative phylogenetic and molecular evolutionary analysis of
RT   tubby-like protein family in Arabidopsis, rice, and poplar.";
RL   Genomics 92:246-253(2008).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q10LG8-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q10LG8-2; Sequence=VSP_035469;
CC   -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:18620041}.
CC   -!- SIMILARITY: Belongs to the TUB family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF12031.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DP000009; ABF95934.1; -; Genomic_DNA.
DR   EMBL; DP000009; ABF95936.1; -; Genomic_DNA.
DR   EMBL; AP008209; BAF12031.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM000140; EAZ26915.1; -; Genomic_DNA.
DR   EMBL; AK102370; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015631451.1; XM_015775965.1. [Q10LG8-1]
DR   RefSeq; XP_015631452.1; XM_015775966.1. [Q10LG8-1]
DR   AlphaFoldDB; Q10LG8; -.
DR   SMR; Q10LG8; -.
DR   STRING; 4530.OS03T0351400-01; -.
DR   PaxDb; Q10LG8; -.
DR   PRIDE; Q10LG8; -.
DR   GeneID; 4332845; -.
DR   KEGG; osa:4332845; -.
DR   eggNOG; KOG2502; Eukaryota.
DR   InParanoid; Q10LG8; -.
DR   OrthoDB; 1445357at2759; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000007752; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Gene3D; 3.20.90.10; -; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR025659; Tubby-like_C.
DR   InterPro; IPR000007; Tubby_C.
DR   InterPro; IPR018066; Tubby_C_CS.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF01167; Tub; 1.
DR   PRINTS; PR01573; SUPERTUBBY.
DR   SUPFAM; SSF54518; SSF54518; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS01200; TUB_1; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..403
FT                   /note="Tubby-like F-box protein 6"
FT                   /id="PRO_0000351125"
FT   DOMAIN          50..105
FT                   /note="F-box"
FT   VAR_SEQ         1..172
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_035469"
SQ   SEQUENCE   403 AA;  44887 MW;  8B099E3896C82D74 CRC64;
     MSFRSLIQEM RDEFGSISRH SLRSRSHRGG GGAPRVAAVG PAEAAAMQQS CWAQLPPELL
     REVLVRIEES EVWWPSRRDV VACAGVCRSW RGITKEIVRV PEASGKLTFP ISLKQPGPRD
     GTLKCFIRRN RTTQTYYLYI GLTEALADDG KFLLAARKCR KPTCTDYLIS LDMSDMSKGS
     NTYIGKLRSN FLGTKFTVYD AHPPYDGAVV SKSRSARVVG LNQVSPRVPA GNYPVSHISY
     ELNVLGARGP RRMNCIMDSI PTSAVQEGGK APTQTEFPLS GLDSFPSISF FRSKSARIDS
     ATSQLSTQKE EKLVLKNKSP RWHEQLQCWC LNFRGRVTVA SVKNFQLVAS DENGPTNQEQ
     DKVILQFGKI GKDLFTMDYR YPISAFQSFA ICLSSFDTKI ACE