ID   TLP_SENDI               Reviewed;          55 AA.
AC   P84334;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JAN-2010, sequence version 2.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Thaumatin-like protein;
DE            Short=CdTLP;
DE   Flags: Fragments;
OS   Senna didymobotrya (Popcorn cassia) (Cassia didymobotrya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Caesalpinioideae; Cassia clade; Senna.
OX   NCBI_TaxID=72401;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, INDUCTION, SUBCELLULAR LOCATION, AND MASS
RP   SPECTROMETRY.
RX   PubMed=17056265; DOI=10.1016/j.plaphy.2006.09.008;
RA   Vitali A., Pacini L., Bordi E., De Mori P., Pucillo L., Maras B., Botta B.,
RA   Brancaccio A., Giardina B.;
RT   "Purification and characterization of an antifungal thaumatin-like protein
RT   from Cassia didymobotrya cell culture.";
RL   Plant Physiol. Biochem. 44:604-610(2006).
CC   -!- FUNCTION: Has antifungal activity against C.albicans 586 (EC(50)=6.2
CC       uM), C.parapsilosis ATCC 22019 (EC(50)=2.2 uM), C.krusei ATCC 14243
CC       (EC(50)=2.5 uM) and C.krusei 80 (EC(50)=5.4 uM). Has no activity
CC       against C.neoformans, C.tropicalis or T.glabrata.
CC       {ECO:0000269|PubMed:17056265}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17056265}.
CC   -!- INDUCTION: By salicylic acid and by laminarin oligosaccharides.
CC       {ECO:0000269|PubMed:17056265}.
CC   -!- MASS SPECTROMETRY: Mass=23035.9; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:17056265};
CC   -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00699}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P84334; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.110.10; -; 1.
DR   InterPro; IPR037176; Osmotin/thaumatin-like_sf.
DR   InterPro; IPR001938; Thaumatin.
DR   PANTHER; PTHR31048; PTHR31048; 1.
DR   SUPFAM; SSF49870; SSF49870; 1.
DR   PROSITE; PS51367; THAUMATIN_2; 1.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Disulfide bond; Fungicide;
KW   Secreted.
FT   CHAIN           1..>55
FT                   /note="Thaumatin-like protein"
FT                   /id="PRO_0000096225"
FT   DISULFID        9..?
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT   NON_CONS        40..41
FT                   /evidence="ECO:0000305"
FT   NON_TER         55
SQ   SEQUENCE   55 AA;  5692 MW;  064530D6D51ECC2D CRC64;
     ATITFTNKCT RTVWPGTLTG DQKPQLSKTG FELASGVSTR GAAPPATLIE LTVAS